Searchable abstracts of presentations at key conferences in endocrinology

ea0015p71 | Clinical practice/governance and case reports | SFEBES2008

Prolonged oestrogen release from oestrogen implants

Kennedy Amy , Dale Jane

Oestrogen implants are one method of delivering hormone replacement therapy to post-menopausal women. The use of such implants has been associated with the phenomenon of tachyphylaxis, where menopausal symptoms return before the next implant is due, even in the presence of normal or high serum oestrodiol levels. It has been suggested that intervals as long as one year should be left between implants and that trough oestrogen levels should be measured prior to implantation....

ea0025p15 | Bone | SFEBES2011

Parathyroid hormone concentrations in proton pump inhibitor induced hypomagnesaemia

Kennedy Amy , Gittoes Neil , Ayuk John

Severe hypomagnesaemia associated with the use of proton pump inhibitors (PPIs) is now increasingly recognised. The exact underlying mechanism is unclear but is likely to involve altered intestinal absorption of magnesium ions. Hypomagnesaemia from any cause results in functional hypoparathyroidism. PTH levels vary widely in reported cases of hypomagnesaemia associated with the use of PPIs. We examined PTH levels in patients admitted to hospital with severe (Mg<0.4 mmol/l)...

ea0022p238 | Clinical case reports and clinical practice | ECE2010

A case of severe hypocalcaemia post liver transplantation

Hughes David , Kennedy Amy , Cooper Mark

Background: There are over 650 liver transplants performed in the UK each year and about 5000 throughout Europe. After transplantation patients suffer from bone loss due to multiple factors. We present a unique case of severe Vitamin D deficiency resulting in life threatening hypocalcaemia following liver transplantation.Case: A 65-year-old Indian lady underwent an uncomplicated liver transplant, for hepatocellular carcinoma related to Hepatitis C. Pre a...

ea0028p105 | Clinical practice/governance and case reports | SFEBES2012

Diagnostic dilemmas in patients presenting with large adrenal masses – 2 case reports

Mathew Anna , Kennedy Amy , Basu Ansu , De Parijat

The presentation of a patient with an adrenal tumour often causes diagnostic difficulty for the endocrinologist. Adrenal tumours are rare occurrences, particularly when large in size. We present two cases, where large adrenal tumours were found in inpatients on CT scanning and discuss the difficulties which arose in each case when attempting to obtain a definitive diagnosis. Case 1 A 38 year old Bangladeshi woman was being investigated for fevers, sweats and pancytopaenia. She...

ea0021p114 | Clinical practice/governance and case reports | SFEBES2009

The endocrine consequences of stem cell transplantation

Kennedy Amy , Nunnick Jane , Clark Fiona , Craddock Charles , Toogood Andrew

Over the last 10 years there have been significant advances in stem cell transplantation (SCT) in adults for haematological malignancies leading to improved survival. Conditioning regimes prior to transplantation often utilise high dose chemotherapy and/or total body irradiation (TBI). Significant endocrinopathies have been reported amongst children undergoing SCT. We report the effect of SCT during adult life on endocrine function.Basal hormone levels w...