Endocrine Abstracts

Introduction: Thyroid carcinomas (TC) are rare; the incidence in the French Marne-Ardennnes thyroid registry is 10/100.000 in 2010. The 10 year survival rate is greater than 90%. Nevertheless some TC are refractory to conventional therapy.Aim of the study: To describe frequency and clinical features of refractory TC (RTC).Patients and methods: Retrospectiv study from the database of the registry. 1427 patients with TC were diagnose...

Pregnancy is associated with an increased risk of tumor growth in macroprolactinoma leading to discuss surgery in such cases.Objectives: Impact of pregnancy on prolactin secretion and tumor growth in a cohort of women with macroprolactinoma, including large tumors >20 mm, and medically treated.Methods: Retrospective study of all the women with macroprolactinomas diagnosed in two university hospitals, treated by dopamine agonist...

Objectives: Long-term results of medical treatment of macroprolactinoma in children and adolescents (<20 years).Patients and methods: Retrospective analysis of all the cases of macroprolactinoma occurring in children and adolescents, medically treated in two university centers.Results: 38 patients, 25 girls 13 boys, age at diagnosis: 15.7±2.8 years (only two cases before 12 years). At diagnosis, 2/3 presented with headache...