Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.20.01 | Pituitary – Hypopituitarism | ECE2015

Reduced mortality due to malignant neoplasms in patients receiving long-term GH replacement therapy – a Swedish study based on more than 4000 patient-years

Olsson Daniel S , Nilsson Anna G , Trimpou Penelope , Bengtsson Bengt-AEke , Andersson Eva , Johannsson Gudmundur

Patients with hypopituitarism and untreated growth hormone (GH) deficiency have excess mortality. GH replacement therapy (GHRT) has many beneficial effects, but its impact on mortality has not been proven and there are still safety concerns regarding the potential cancer risk. We have therefore studied the mortality in non-functioning pituitary adenoma (NFPA) patients with and without GHRT. Only patients with NFPA were studied in order to eliminate the influence of the aetiolo...

ea0041oc13.3 | Pituitary Clinical | ECE2016

Increased glucocorticoid replacement doses are associated with excess mortality in patients with non-functioning pituitary adenoma

Hammarstrand Casper , Hallen Tobias , Andersson Eva , Skoglund Thomas , Nilsson Anna G , Ragnarsson Oskar , Johannsson Gudmundur , Olsson Daniel S

Background: Patients with secondary adrenal insufficiency have an excess mortality. Data concerning the influence of the glucocorticoid replacement regime on mortality is sparse.Objective: To investigate if the total daily dose of glucocorticoid replacement has an effect on mortality in patients with non-functioning pituitary adenoma (NFPA).Method: Patients with NFPA treated for hypopituitarism in the western region of Sweden were ...

ea0049gp9 | Adrenal 1 | ECE2017

Mortality is increased in patients with Cushing’s disease in long-term remission: A nation-wide study

Chantzichristos Dimitrios , Papakokkinou Eleni , Dahlqvist Per , Segerstedt Elin , Olsson Tommy , Berinder Katarina , Hoybye Charlotte , Bensing Sophie , Engstrom Britt Eden , Burman Pia , Folin Cecilia , Erfurth Eva Marie , Wahlberg Jeanette , Ekman Bertil , Schwarcz Erik , Bryngelsson Ing-Liss , Andersson Eva , Johannsson Gudmundur , Olsson Daniel S , Ragnarsson Oskar

Background: It is still undetermined whether patients with Cushing’s disease (CD) in remission have an increased mortality. Most previous studies are limited by small numbers of patients and/or short follow-up time.Objective: To study mortality in a nation-wide cohort of patients with CD during long-term follow-up.Methods: Patients with ICD codes for Cushing’s syndrome and/or CD, between 1987 and 2013, were identified in ...