Searchable abstracts of presentations at key conferences in endocrinology

ea0064009 | Risk of Malignancy of the Thyroid Nodule Evaluated by Scintigraphy | BES2019

Risk of Malignancy of the Thyroid Nodule Evaluated by Scintigraphy

Elias De Meyst , Bert Bravenboer , Marleen Keyaerts , Steven Raeymaeckers , Brigitte Velkeniers , Corina Andreescu

Background: Thyroid nodules are a common finding in clinical practice. Among classic risk factors for thyroid cancer, thyroid scintigraphy has traditionally been attributed prognostic value, with cold nodules implying greater risk. However, research supporting this assumption is of considerable age and possibly influenced by selection bias. In this study, we aimed to calculate the risk of malignancy in cold and hot nodules.Material and Methods: All thyro...

ea0037ep37 | Adrenal cortex | ECE2015

Pregnancy-induced Cushing's syndrome

Andreescu Corina , Hofland Leo , Hofland Hans , Looijenga Leendert , de Herder Wouter , Feelders Richard

CushingÂ’s syndrome (CS) during pregnancy is a rare metabolic condition with only a few cases reported in the literature. Misdiagnosis of CS is common because of the overlapping features of fatigue, weight gain, striae, and emotional changes that occur during normal pregnancy. The clinical presentation together with laboratory and imaging findings help to make a diagnosis. However, changes in maternal hormones and their binding proteins complicate assessment of the normal ...

ea0056gp211 | Pituitary Clinical | ECE2018

A systematic review and meta-analysis of endocrine-related adverse events associated with immune checkpoint inhibitors

de Filette Jeroen , Andreescu Corina , Cools Filip , Bravenboer Bert , Velkeniers Brigitte

Background: Monoclonal antibodies targeting CTLA-4 and PD-1/PD-L1 are promising for a wide range of advanced malignacies. These immune checkpoint inhibitors (ICI) provoke endocrine adverse events including hypopituitarism and primary thyroid disease.Methods: PubMed was searched through August 22nd, 2017, for relevant articles on endocrinopathies and ICI, by two reviewers independently (J.d.F. and C.A.). The weighted incidence and odds-ratio were estimate...

ea0064038 | Pheochromocytoma-induced Takotsubo syndrome: when you hear hoofbeats, it may be a zebra! | BES2019

Pheochromocytoma-induced Takotsubo syndrome: when you hear hoofbeats, it may be a zebra!

Jerrold Spapen , Jeroen de Filette , Bastiaan Sol , Aan Kharagjitsing , Brigitte Velkeniers , Bert Bravenboer , Stijn Lochy , Corina Andreescu

Pheochromocytoma is a rare catecholamine-secreting tumor with variable clinical manifestations. A possible cardiac presentation is acute left ventricular wall motion abnormality in the heart also known as the Takotsubo syndrome. Takotsubo stress cardiomyopathy was first described in 1990 in Japan and current knowledge remains limited. We report a case of pheochromocytoma-induced Takotsubo syndrome. A 43-year-old woman acutely developed nausea, severe chest pain, and dyspnoea d...