Searchable abstracts of presentations at key conferences in endocrinology

ea0022s2.1 | Endocrine aspects about the metabolic syndrome | ECE2010

Brain–adipose and brain–liver connections in the metabolic syndrome

Fliers Eric , Klieverik Lars , Yi Chun-Xia , Ackermans Mariette , Kalsbeek Andries

Pre-autonomic neurons in the hypothalamic paraventricular nucleus (PVN) project to sympathetic and parasympathetic motor nuclei in the brain stem, from where the liver and white adipose tissue (WAT) are innervated by both branches of the autonomic nervous system (ANS). Studies by our group and by others have shown that these neural pathways modulate glucose and lipid metabolism in liver and WAT. Given the abundant thyroid hormone receptor (TR) expression in the PVN we hypothes...

ea0063p652 | Interdisciplinary Endocrinology 1 | ECE2019

Restoring the sleep disruption by blue light emitting screen use in adolescents: a randomized controlled trial

Meijden Wisse P van der , Stenvers Dirk Jan , Kerkhof Linda van , Nierop Lotte van , Steeg Harry van , Bisschop Peter H , Someren Eus J van , Kalsbeek Andries

Introduction: Adolescents spend much time using blue-light emitting screen devices such as smartphones, tablets and computers. Blue light affects the central circadian clock in the suprachiasmatic nucleus (SCN) as well as melatonin secretion by the pineal gland. Screen use in adolescents strongly associates with reduced sleep quality and sleep duration. However, there is a lack of intervention studies that reduce blue light exposure due to screen use in adolescents.<p clas...