Searchable abstracts of presentations at key conferences in endocrinology

ea0090p763 | Thyroid | ECE2023

Long term effects of 0.1 mg Recombinant Human Thyrotropin-Stimulated fix dose of radioiodine therapy in patients with recurrent multinodular goiter after surgery. A 10 year follow-up study

Angelopoulos Nikolaos , Iakovou Ioannis , Effraimidis Grigoris , Livadas Sarantis

Background: Several treatment options exist after thyroid malignancy has been ruled out in patients with multinodular goiter (MG). Surgery efficiently reduces the goiter size but carries a risk of both surgical and anesthetic complications while in recent years, levothyroxine suppressive therapy has been abounded. I131 therapy is the only nonsurgical alternative; however, the effectiveness diminishes with increasing goiter size and depends on iodine sufficiency in some areas. ...

ea0090ep215 | Calcium and Bone | ECE2023

Short-term treatment with 2000IU of cholecalciferol in patients with secondary hyperparathyroidism due to vitamin d insufficiency

Angelopoulos Nikolaos , Boniakos Anastasios , Karras Spyridon , Paparodis Rodis , Livadas Sarantis

Introduction: Conventional treatment of secondary hyperparathyroidism (SHP) requires supplementation of vitamin d analogues combined with calcium however several studies have reported concerns regarding the safety of calcium supplements particularly in the long term. If vitamin d without concomitant calcium supplementation is sufficient to prompt a fall in the parathyroid hormone (PTH) is still not known with certainty. The purpose of our study was to investigate if vitamin d ...

ea0084op-06-30 | Oral Session 6: Hypothyroidism | ETA2022

Levothyroxine replacement therapy overuse and factors guiding successful treatment discontinuation: short and long-term observation data of a large cohort

Livadas Sarantis , Androulakis Ioannis , Angelopoulos Nikolaos , Anagnostis Panagiotis , Paparodis Rodis , Boniakos Anastasios , Askitis Dimitrios , Duntas Leonidas

Background: Levothyroxine (LT4Rx) is one of the most prescribed drugs worldwide the vast majority of patients receive long-term treatment. However, in a recent study of 291 subjects, it was found that 60% were euthyroid 2 months after LT4-Rx discontinuation1.Aim of the study: A prospective clinical cohort follow-up study was carried out. In 688 subjects (82% females) aged 48.01±15.96 (range 17-84years) with 8.59±6.98 years on LT4Rx witho...

ea0090p508 | Thyroid | ECE2023

The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?

Angelopoulos Nikolaos , Paparodis Rodis , Androulakis Ioannis , Boniakos Anastasios , Karras Spyridon , Livadas Sarantis

Background: In the last decade, the combination of the widespread use of streptavidin-biotin technology and biotin–containing supplements (BCS) in the daily clinical practice, have led to numerous reports of erroneous hormone immunoassay results. However, there are no studies assessing the clinical and biochemical significance of that phenomenon, when treating patients with hypothyroidism. Therefore, a prospective study was designed to investigate the potential alteration...