Endocrine Abstracts

Incidentally discovered adrenal nodules are an increasingly common reason for referral into the endocrine clinic. Assessment includes a hormonal work-up to look for endocrine function, and reviewing the size and radiological characteristics of the lesion. Some nodules have benign radiological features (less than 10 HU on an unenhanced CT scan), whilst others are radiologically indeterminate (more than 10 HU). We worry about missing a malignant process. The research data and in...

Incidentally discovered adrenal nodules are an increasingly common reason for referral into the endocrine clinic. Assessment includes a hormonal work-up to look for endocrine function, and reviewing the size and radiological characteristics of the lesion. Some nodules have benign radiological features (less than 10 HU on an unenhanced CT scan), whilst others are radiologically indeterminate (more than 10 HU). We worry about missing a malignant process. The research data and in...

‘Functional’ hypothalamic amenorrhoea (FHA) is a common cause of secondary amenorrhoea. A focused history should include a full menstrual history (including hormonal contraception); diet, weight and exercise (including any eating disorder); any significant stressors; the woman’s current situation in relation to contraception and fertility plans; a personal or family history of a lack of sense of smell (suggesting Kallmann syndrome); and any family history of del...

Childhood cancer survivors are a growing population. Lifelong endocrine follow up is essential for brain tumour and bone marrow transplant survivors who received radiotherapy. Patients attending the ‘late effects’ clinic have investigations coordinated with an annual appointment including endocrine bloods, urine protein:creatinine ratio, blood pressure and weight. The Covid-19 pandemic necessitated appointments to be telephone. Patients were asked to arrange their an...

Introduction: Adrenal myelolipomas are rare benign tumours consisting of fat and haematopoietic elements. We present an adult male patient with congenital adrenal hyperplasia (CAH) with an incidental diagnosis of bilateral adrenal myelolipomas, resulting in an improvement in adherence to treatment, but uncertainty regarding his future management.Case history: 53 year old man with known CAH was referred into the endocrine clinic, historically requiring la...

Case history: A 28-year-old gentleman was referred with symptoms of memory fog, difficulty with concentration, mood disturbance and fatigue. His thyroid function tests had been stable but abnormal for over 8 years, with a normal FT4 between 17–19 pmol/l (12–22 pmol/l), FT3 5.6 pmol/l (3.1–6.8 pmol/l) and an elevated TSH between 12–16 mu/l (0.27–4.2 mu/l). He had no family history of thyroid disease. He was clinically euthyroid. His weight had remained ...

Introduction: Thyroid storm is a rare endocrine emergency associated with the reported mortality rate ranging from 10 to 20%. We discussed the management of two cases of thyroid storm with different outcomes. It also showed the successful use of ECMO in the management of severe hyperthyroidism related cardiomyopathy and circulatory collapse.Case History 1: A 36 years old female with known history of Graves’ disease, presented with palpitations and s...

Section 1: Case history: A 53 year old male of Chinese ethnicity presented to hospital with a fall and a long lie. He had a heavy meal for dinner, and he fell later in the evening after standing from the sofa. He lacked strength in his limbs and could not stand up again. He was on the floor for 7 hours before he could shuffle his way to the phone and call for help. On examination he had MRC grade. power in the proximal arms and MRC grade. hip. flexion. Sensation was normal. He...

Method: We carried out a retrospective audit of baseline data for patients under our care with primary hyperparathyroidism on cinacalcet therapy, against the NHS England Clinical Commissioning Policy (July 2016). Patients with secondary hypercalcaemia due to end stage renal failure were excluded.Results: 40 patients were identified, 9 men and 31 women, with an age range of 32–89 years (median age 78). 3 patients were under 50 ...

Method: We carried out a retrospective audit of baseline data for patients under our care with primary hyperparathyroidism on cinacalcet therapy, against the NHS England Clinical Commissioning Policy (July 2016). Patients with secondary hypercalcaemia due to end stage renal failure were excluded.Results: 40 patients were identified, 9 men and 31 women, with an age range of 32–89 years (median age 78). 3 patients were under 50 ...