Searchable abstracts of presentations at key conferences in endocrinology

ea0056p634 | Clinical case reports - Thyroid/Others | ECE2018

When it is the time of prophylactic thyroidectomy to children with medullary thyroid cancer with RET proto-oncogene Cys634Trp mutation in a family with multiple endocrine neoplasia type 2A

Galesanu Corina , Niculescu Dan , Apostu Luminita , Romeo Galesanu Mihail

Background: Almost all patients with Multiple Endocrine Neoplasia, type 2A (MEN 2A) have MTC. C-cell hyperplasia develops early in life and can be viewed as the precursor lesion for MTC. Children with MEN2A who have a total early thyroidectomy have an excellent chance of remaining disease-free.Objectives: To follow-up the children with RET mutation in a family with MEN2A.Methods: We report a family with MEN2A in which the first pat...

ea0022p213 | Clinical case reports and clinical practice | ECE2010

The role of octreotide in the management of young patients with acromegaly

Florescu Alexandru , Grozavu Ilinka , Lisnic Natalia , Apostu Luminita , Moisii Liliana , Poeata Ion , Galesanu Corina

The last decade has provided major progress in the development of highly specific and selective pharmacological agents that have facilitated a more aggressive approach to the treatment of patients with acromegaly. Initial transsphenoidal surgery still appears to be the first line of treatment, but in many cases the biochemical cure targets are not reached and the patient needs adjuvant therapy. Somatostatin analogues have become the mainstay of the medical treatment of acromeg...

ea0049ep1360 | Thyroid (non-cancer) | ECE2017

Mirela Tirnovan1, Anamaria Bursuc1, Alina Daniela Belceanu1, Adina Manolachie1, Ioana Armasu1, Iulia Crumpei1, Georgiana Constantinescu1, Luminita Apostu2, Carmen Vulpoi1

Tirnovan Mirela , Bursuc Anamaria , Belceanu Alina Daniela , Armasu Ioana , Crumpei Iulia , Manolachie Adina , Apostu Luminita , Vulpoi Carmen

Introduction: Many causes of malabsorbtion of levothyroxine (LT4) in patients with hypothyroidism have been thoroughly described in literature. Pseudomalabsorption, poor compliance of the patient is most common cause of failure of LT4 and/or liothyronine (LT3) treatment.Case report: 27 years old woman, normopondeal, presented from the age of 11 years for short stature. Further investigations found pluritrope pituitary insufficiency ...

ea0022p212 | Clinical case reports and clinical practice | ECE2010

The difficulties of Cushing' s disease – case report

Grozavu Ilinka-Andreea , Florescu Alexandru , Lisnic Natalia , Apostu Luminita , Bostaca Tamara , Moisii Liliana , Niculescu Dan , Galesanu Corina

Cushing’s disease is relatively rare and affects most commonly adults aged 20 to 40. It is associated with high morbidity and mortality; early detection and diagnosis of Cushing’s disease may lead to decreased this two facts and improved quality of life.We present a 32-year-old man with abdominal purple striae, central obesity with typical ‘moon face’ and oscillatory blood pressure values.Hormonal exams revealed...