Searchable abstracts of presentations at key conferences in endocrinology

ea0063p332 | Reproductive Endocrinology 1 | ECE2019

Natural estradiol in combined oral contraceptive has a favorable inflammation and lipid profile compared with preparation containing ethinyl estradiol– a randomized controlled trial

Kangasniemi Marika , Haverinen Annina , Heikinheimo Oskari , Luiro Kaisu , Arffman Riikka , Tapanainen Juha , Piltonen Terhi

Study question: Does the combination of estradiol valerate (EV) and dienogest (DNG) have favorable effects on inflammation and lipids compared with ethinyl estradiol (EE) + DNG?What is known already: Use of combined oral contraceptives (COCs) increases HDL-cholesterol and triglycerides and promotes low-grade inflammation. The metabolic effects of COCs depend on both estrogen and progestin components. To our knowledge this is the first study comparing COC...

ea0081rc12.8 | Rapid Communications 12: Reproductive and Developmental Endocrinology | ECE2022

Ethinyl estradiol in a combined contraceptive exerts greater effect on serum proteome than estradiol valerate – a randomized trial

Kangasniemi Marika , Arffman Riikka , Joenvaara Sakari , Haverinen Annina , Luiro Kaisu , Tohmola Tiialotta , Renkonen Risto , Heikinheimo Oskari , Tapanainen Juha , Piltonen Terhi

Background: Combined oral contraceptives (COC) are known to have multiple beneficial effects besides contraception, but also cause some unwanted health outcomes. They interfere, for example, with metabolism, inflammation, hepatic protein synthesis and blood coagulation. COCs containing natural estrogens have recently been developed, yet little is known about their non-contraceptive effects compared to conventional COCs with ethinyl estradiol (EE). The aim of this study was to ...

ea0070aep784 | Reproductive and Developmental Endocrinology | ECE2020

Polycystic ovary syndrome is burdened with a high comorbidity rate and medication use independent of BMI: A longitudinal community based study

Kujanpää Linda , Piltonen Terhi , Arffman Riikka , Pesonen Paula , Morin-Papunen Laure , Tapanainen Juha , Franks Stephen , Järvelin Marjo-Riitta

Objective: To investigate comorbidity rate, symptoms, overall morbidity, medication useand use of health care services among women with polycystic ovary syndrome (PCOS).Design: Community-based prospective cohort study.Patients: Womenreporting oligo/amenorrhea and hirsutism at age 31 and/or PCOS diagnosis by age 46 (n = 280) and controls without PCOS related symptoms or diagnosis (n = 1573) in the Northern ...