Endocrine Abstracts

Introduction: Dulaglutide (Trulicity®) is a long-acting GLP-1 agonist that received US Food and Drug Administration (FDA) approval in 2014. Dulaglutide is a large sized molecule, which limits its renal clearance. This allows for once weekly dosing; which might improve patient compliance significantly. Extensive Phase III study data have been published with regard to dulaglutide, much of which was part of the AWARD studies, which provide evidence for its use in ...

Introduction: Klinefelter syndrome (KS) is the most common congenital abnormality causing primary hypogonadism. KS has a tendency for hypercoagulability.Case report: A 48 year old man diagnosed as having KS during the sterility test was admitted to our hospital emergency department after suffering a syncopal episode at work. He complained of difficulty breathing during the last two weeks and he was receiving bronchodilator therapy. He had suffered deep v...