Endocrine Abstracts

Purpose: The aim of this study was to evaluate the association and frequency of thyroid autoimmunity in patients with empty sella syndrome and to evaluate the possible effects of thyroid auto-antibodies on clinical and laboratory findings in patients with empty sella syndrome.Materials and methods: We recruited 93 patients (female) and 22 male patients (mean age 55.51±14.82) who were admitted to the Endocrinology Clinic of Erzurum Regional Training ...

Introduction and aim: The incidence of atherosclerotic vascular disease is high in obesity. Our aim is to determine the mean platelet volume (MPV) as a new indicator of atherosclerosis in morbid obesity.Materials and methods: Thirty-three patients with morbid obesity who applied to endocrinology department (mean age 41.5±11.3 years, body weight 118.2±16.9 kg and BMI: 45.9±7.2 kg/m2) and 39 age-matched (mean age 35.3±13.1 ye...

Aim: İmpaired glucose tolerance and hyperinsulinism/insulin resistance frequently accompany by acromegaly. NLO (Neutrophile lymphocyte ratio) is demonstrated as a simple indicator of systemic inflammation and it is also known that NLO is associated with atherosclerosis progression in coronary artery and a risk factor in coroner artery disease. In this study, we intend to search the association between both coronary atherosclerosis seen frequently in patients diagnosed wi...

Background: Parathyroid hormone (PTH) is a key regulator of mineral metabolism, the homeostasis of calcium, phospate, vitamin D and bone turnover. Hypoparathyroidism is a rare disease characterized by hypocalceamia with inappropriately low plasma levels of PTH. Mean platelet volume (MPV) is the measure of platelet size. Increased MPV has been associated with cardiovascular risk.Objective: In our preliminary study, we aim to show that untreated hypoparath...

Aim: In a previous study, we demonstrated elevated mean platelet volume in isolated hypogonadotrophic hypogonadism (IHH) is associated with high cardiovascular risk. Monocyte count/HDL-cholesterol ratio (MHR) is a new inflammatory marker showing cardiovascular risk. The purpose of this study is to evaluate (MHR) in men with hypogonadotrophic hypogonadism.Method: This study includes 31 men with isolated hypogonadotrophic hypogonadism without previous trea...

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

Aim: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are prognostic markers of differentiated thyroid cancers. In our study we evaluated NLR, PLR and C-reactive protein for predicting the occurence of differentiated thyroid cancer. This is the first study that compares NLR and PLR to C-reactive protein indifferantiated thyroid cancer not only papillary cancer but also folliculer cancer.Materials and Method: This study includes 51 pa...

Aim: The risk of cardiovascular mortality is high in patients with acromegaly. In this study, we intent to evaluate serum lipid profile in patients newly diagnosed with acromegaly and determine its association with increased growth hormone (gh) and insulin like growth factor-1 (igf-1) levels.Material and method: This study includes 57 patients newly diagnosed with acromegaly in our hospital (mean age 44.1±13.8 years; mean bmi 29.6±5.4 kg/m...

Purpose: The association between differentiated thyroid cancers and autoimmune thyroid diseases is well known. Therefore, we aimed to investigate the importance of thyroid peroxidase antibody (anti-TPO) and thyroglobulin antibody (Anti-Tg) in patients followed with the diagnosis of Hashimoto’s thyroiditis regarding the development of differentiated thyroid cancer.Methods: A total of 56 patients including 22 Hashimoto’s thyroiditis patients oper...