Endocrine Abstracts

The specialist weight management service (SWMS) is a tier 3 service offered to patients who meet a criterion of raised BMI with or without comorbidities. It is a multi-disciplinary service made up of physician, GPwSI, dietitians, physiotherapist, psychologists and health trainers. Approximately 40% of the patient within the service has type 2 diabetes. As part of a quality improvement pilot study a diabetes specialist nurse was introduced to the team. Patients were seen in an ...

Introduction: With the increasing incidence of obesity worldwide, there is growing demand for bariatric surgery which carries its own risks. Post Bariatric hyperinsulinemic hypoglycaemia is rare but yet challenging condition to manage.Case Presentation: In this paper we are describing the case of a 54 years old female who presented with severe hypoglycaemia symptoms 10 months post her RYGB surgery. She underwent an oral glucose tolerance test through whi...

Background: The COVID19 pandemic greatly affected the delivery of outpatient clinics. Tier 3 specialist weight management services (SWMS) aim to help obese patients lose weight through holistic lifestyle modification delivered by a multidisciplinary team consisting of specialist physicians, dieticians, physiotherapists, psychologists, and support workers. Prior to the pandemic, the service was delivered mainly through in person consultations. The nature of the pandemic necessi...

Background: Maturity-onset diabetes of the young (MODY) is a group of 13 monogenic forms of diabetes transmitted in an autosomal dominant pattern and is characterized by a primary defect in pancreatic β-cell function. This disease has an early onset, usually before 25 years of age. It may present with mild asymptomatic hyperglycemia with progressive development to clinical diabetes mellitus. First-line treatment relies on sulphonylureas or insulin according to MODY subtyp...

Objective: To determine whether people with an incidentally discovered adrenal mass are investigated according to regional and global standards (AACE guidelines); to determine the frequency of autonomous endocrine function.Methods: We did a retrospective analysis of clinical, pathology, and radiology records from January 2007 to December 2011. Patients were included if they were seen in the outpatient clinic for evaluation of an adrenal mass >1 cm in...

Introduction: We submit a rare presentation of pheaochromocytoma in pregnanacy, diagnosed just before delivery, posing complex management difficulties.Case presentationA 24-year-old primipara had headache, hypertension and visual disturbance but without any palpitations or diaphoresis. Her headache was persistent during pregnancy. Investigations at 39 weeks of gestation showed normal plasma Normetadrenaline at 885.0 (120–1180)...

Omnitrope is a biosimilar growth hormone (GH) preparation with a lower acquisition cost than other GH preparations. We switched adult patients with growth hormone deficiency treated with Genotropin (n=14, age 59.2±13.7 [mean±SD] yrs, 8 male) to Omnitrope at an equivalent dose. There followed titration visits every month for 3 months then visits every 3 months until 9 months. GH dose (0.5±0.0 vs 0.5±0.0 mg [mean±SD],...

A 66-year-old HIV positive male presented to gastroeneterologist with a 2 months history of severe fatigue, weight loss, dizziness and nausea. He had background of ulcerative colitis which was quiescent and he has not received steroids for more than 12 months. Baseline blood results revealed normal biochemistry with mild normocytic anaemia, neutropaenia and lymphopaenia. As there was a high clinical suspicion of adrenal insufficiency, the short synacthen test was performed whi...

Introduction: We submit a rare presentation of round blue cell pituitary tumour complicated by cranial diabetes insipidus following transphenoidal surgery.Case history: 47-year-old lady with severe headache was diagnosed with a 10 mm non functioning pituitary macro adenoma. Initial plan for conservative management was revised as she developed sixth cranial nerve palsy, bi temporal hemianopia and rapidly enlarging pituitary tumour to 20×18×19 mm...

Background: Autoimmune Graves’ disease is the most common cause of hyperthyroidism. Medical management of Graves’ thyrotoxicosis with thionamides is complicated by a reported relapse rate of about 60%.Aims: The aims of this study were to determine the relapse rate of patients treated with drugs as first line treatment for Graves’ disease and to assess the impact of patient demographics, serum free T4(fT4) and clinical characteristics on re...