ea0063gp99 | Adrenal and Neuroendocrine - Basic | ECE2019
, Shapiro Igor
, Perge Pal
, Igaz Peter
, Hantel Constanze
Current systemic treatments are not satisfying for the treatment of adrenocortical carcinoma (ACC). However, translation of preclinically promising approaches were often disappointing indicating that existing tumor models might have inadequately predicted clinical applicability. Thus, our workgroup initiated a comparative drug screen of relevant chemotherapies and therapies targeting IGFR, EGFR, VEGFR/PDGFR and Wnt signalling pathway in the classical NCI-H295R and recently dev...