Searchable abstracts of presentations at key conferences in endocrinology

ea0004p84 | Steroids | SFE2002

THE EFFECT OF GONADECTOMY ON THE TWENTY-FOUR HOUR CORTICOSTERONE PROFILE AND STRESS RESPONSE OF MALE AND FEMALE RATS

Seale J , Woods S , Atkinson H , Bate E , Jessop D , Lightman S , Harbuz M

Enhanced corticosterone release by female compared to male rats under basal and stress conditions has been frequently evidenced (1). The demonstration that gonadectomy enhances stress-induced corticosterone secretion in male rats (2) but reduces such levels in female rats (3) suggests a causal association between gonadal steroids and corticosterone release. The present study examined the corticosterone profile of intact and gonadectomised female and male rats under basal and s...