Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep13 | Adrenal cortex | ECE2015

Does IGF-1 have a role in ethiopathogenesis of adrenal incidentaloma?

Bahadir Cigdem Tura , Atmaca Hulusi

Objectıve: Due to increased usage of imaging modalities today, incidence of adrenal incidentaloma (AI) has increased. Insulin resistance is considered as the etiopathogenic mechanism. Since both insulin and IGF-1 are capable of interacting with same receptors, we aimed to investigate whether IGF-1 has a role in development of adrenal incidentaloma.Materıals and method: 50 female patients with nonfunctional adrenal incidentaloma and 55 acromegal...

ea0035p211 | Clinical case reports Pituitary/Adrenal | ECE2014

Can bexarotene be a candidate drug for the medical therapy of Cushing's syndrome?

Atmaca Hulusi , Isikli Gulsen , Senturk Nilgun , Buyukkaya Piltan

We report a patient with mycosis fungoides treated with bexarotene (Targretin), a synthetic retinoid analog with specific affinity for retinoid X receptor. This patient developed hypopituitarism characterized by hypogonadism, hypothyroidism, and hypoadrenalism. Although central hypothyroidism is a common side effect of bexarotene, central hypogonadism, and hypoadrenalism has been reported in one case. Clinicians should have high index of suspicion for hypopituitarism in patien...

ea0032p287 | Clinical case reports - Thyroid / Others | ECE2013

Postmenopausal hirsutism and hyperandrogenemia due to granulosa cell tumor of the ovary

Bahadir Cigdem , Atmaca Aysegul , Atmaca Hulusi , Colak Ramis

Inroduction: Progressive baldness and severe hirsutism associated with granulosa cell tumor of ovaries are rare conditions in women. Reported cases are usually pubertal girls and young women. Here, we report a case of postmenopausal baldness and hirsutism due to granulosa cell tumor of the ovary.Case report: A 62 year-old woman presented with baldness and hirsutism on her face, body and back for 3 years. She had menarche at 14 years and menopause at 52 y...

ea0020p453 | Obesity and Metabolism | ECE2009

A comparison of serum leptin levels and metabolic parameters included serum lipoproteins and glucose homeostasis between national wrestlers and healthy males

Yamaner Faruk , Bayraktaroglu Taner , Atmaca Hulusi , Ziyagil MehmetAkif , Tamer Kemal

Background and aim: Wrestling success depends on power, power endurance, and maximum strength, muscular endurance of short duration, flexibility as well as technique and tactical skills. Weight control and weight loss are also very important issues in the view of wrestling success. In this study, it was aimed to investigate the anthropometric features, serum lipoproteins, glucose homeostasis and leptin levels in Turkish National Senior Wrestlers and healthy sedentary males.</p...

ea0020p642 | Reproduction | ECE2009

Gonadal function in male mountain bikers

Yamaner Faruk , Atmaca Hulusi , Bayraktaroglu Taner , Aydin Mustafa , Aydemir Selim

Objectives: Mountain biking has become increasingly popular worldwide. Mountain bikes, are a common source of significant injuries including chronic overuse injuries affecting the genitourinary tract. Erectile dysfunction and infertility are some of the reported urogenital problems in male riders. Our aim was to evaluate the testicular function in male mountain bikers.Methods: Thirty male professional mountain bikers with a mean age of 23.4±2.5 year...

ea0016p151 | Clinical cases | ECE2008

Two unusual cases with pancytopenia associated with Sheehan's syndrome

Atmaca Hulusi , Bayraktaroglu Taner , Akoz Ayla Gokmen , Koyuncu Birsen Unsal

Introduction: Sheehan’s sydrome was known varying degrees of hypopituitarism due to postpartum ischemic necrosis by different etiologies. We report two case who are presented with pancytopenia which is unusual and rarely observed an important clinical finding associated with Sheehan’s syndrome.Case 1: A 57-year-old woman has complaints of malaise, fatigue, and dyspnea without lymphadenopatia and hepatosplenomagaly. She had excessive bleeding af...

ea0041ep611 | Endocrine tumours and neoplasia | ECE2016

Obstructive sleep apnea syndrome in patients with Cushing’s syndrome

Gokosmanoglu Feyzi , Guzel Aygul , Kan Elif Kılıc , Atmaca Hulusi

Aim: Obstructive sleep apnea syndrome (OSAS) has been studied rarely in patients with Cushing’s syndrome. We investigated the possible association between Cushıng’s syndrome and OSAS in this study.Method: Thirty female patients with newly diagnosed Cushing’s syndrome and 30 female obese control subjects were included in this study. All the participants were evaluated by polysomnography. OSAS was defined as apneahypopnea index (AHI) of...

ea0035p1110 | Thyroid Cancer | ECE2014

Metastatic thyroid papillary microcarcinomas

Bahadir Cigdem Tura , Kan Elif Kilic , Gokosmanoglu Feyzi , Ecemis Gulcin Cengiz , Atmaca Hulusi

Aim: Thyroid papillary carcinomas smaller than 1 cm are called papillary microcarcinomas (PMC). They rarely metastasize to lymph node (LN) and distant areas. The presence of palpable lymphadenopathy at the time of diagnosis shows high risk of recurrence regardless of primary tumor size. We aimed to investigate histopathologic characteristics and recurrence frequency of thyroid PMCs with LN metastasis (LNM).Materials and methods: Thyroid PMC cases with LN...

ea0032p109 | Bone and Osteoporosis | ECE2013

A patient osteogenesis imperfecta with osteoporosis

Ecemis Gulcin Cengiz , Kan Elif Kilic , Bahadir Cigdem Tura , Atmaca Aysegul , Atmaca Hulusi , Colak Ramis

Introduction: Osteogenesis imperfecta (OI) is a congenital, generalized connective tissue disorder characterized by severe osteoporosis and bone fragility. OI is most commonly caused by mutations in genes encoding the α-1 and α-2 chains of type I collagen or proteins involved in posttranslational modification of type I collagen. Although, no controlled studies are done, bisphosphonates are used for the treatment of OI. I.v. bisphosphonates are reported to be more eff...

ea0032p264 | Clinical case reports – Pituitary/Adrenal | ECE2013

Cases with adrenocortical carcinoma

Ecemis Gulcin Cengiz , Kan Elif Kilic , Bahadir Cigdem Tura , Atmaca Aysegul , Atmaca Hulusi , Colak Ramis

Introduction: Adrenocortical carcinoma (ACC) is a rare cancer (estimated incidence, 0.7 to 2.0 cases per 1 million population per year) with a poor prognosis. Even after seemingly complete surgical resection, most patients develop recurrence within 5 years. The 5-year survival rate is <15% among patients with metastatic disease.Methods: We present the results of six patients with adrenocortical carcinoma followed in our clinic....