Endocrine Abstracts

We report a case of two incidental lesions, a benign adrenal schwannoma and cerebral meningioma. There are no cases in the literature to link de-novo adrenal schwannoma and meningioma in patients. This case highlights the importance of multidisciplinary working to ensure expedited management in such cases.A 76 year old gentleman presented to ED with a seizure and a community-acquired pneumonia. Past medical history included atr...

We present a case of a middle-aged lady with clinical features suspicious of Addisons, however an initial false negative short synacthen test (SST), resulted in delay of diagnosis.Case: A 62-year-old lady presented to ED with a month history of generalised malaise, weakness, dizziness and vomiting. She had a background of type2 diabetes mellitus, previous left parathyroidectomy for primary hyperparathyroidism and B-thalassaemia trait. Admission bloods in...

We report a case of two incidental lesions, a benign adrenal schwannoma and cerebral meningioma. There are no cases in the literature to link de-novo adrenal schwannoma and meningioma in patients. This case highlights the importance of multidisciplinary working to ensure expedited management in such cases.A 76 year old gentleman presented to ED with a seizure and a community-acquired pneumonia. Past medical history included atr...

We present a case of a middle-aged lady with clinical features suspicious of Addisons, however an initial false negative short synacthen test (SST), resulted in delay of diagnosis.Case: A 62-year-old lady presented to ED with a month history of generalised malaise, weakness, dizziness and vomiting. She had a background of type2 diabetes mellitus, previous left parathyroidectomy for primary hyperparathyroidism and B-thalassaemia trait. Admission bloods in...

Objective: Hyperprolactinaemia is one of the most common disorders of the hypothalamic-pituitary axis. Endocrine Society guidelines state that a single prolactin measurement in a blood sample obtained at any time of day is adequate to confirm hyperprolactinaemia. However, prolactin levels can be confounded by physiological stimuli, e.g sleep, stress or exercise. Our objective was to assess the clinical significance of prolactin level obta...

A 43 year old Somali woman presented with increasing fatigue, difficulty getting out of her chair and 15 kg weight gain over a one month. Past medical history included paranoid psychosis, nasal congestion due to adenotonsillarhypertrophy, and human immunodeficiency virus (HIV). Her HIV infection was well controlled (viral load <50RNA copies/ml), with excellent immunological reconstitution (CD4 count >500 cells/mm3). Current medicat...

Serum alkaline phophatase (ALP) may be released from various sources, including liver, bone, thyroid, intestine and placenta. Herein, we describe a rare case of an isolated serum ALP rise initially dismissed, and later resulting in an incidental finding of a mediastinal seminoma.A 56-year-old gentleman was referred to the Endocrinology Outpatients by his general practitioner, with a 1-month history of presumed post-viral fatig...

A 22-year-old female first presented in 2008 with a six-month history of galactorrhoea and irregular menses. She had hyperprolactinaemia (2401 mIU/L), a negative macroprolactin screen and her pituitary MRI scan demonstrated a 4 mm microadenoma. Her cannulated prolactin levels were >1500 mIU/L. TFTs, IGF-1, cortisol and remaining pituitary profile were within normal range.Cabergoline was commenced and gradually i...

Objective: Hyperprolactinaemia is one of the most common disorders of the hypothalamic-pituitary axis. Endocrine Society guidelines state that a single prolactin measurement in a blood sample obtained at any time of day is adequate to confirm hyperprolactinaemia. However, prolactin levels can be confounded by physiological stimuli, e.g sleep, stress or exercise. Our objective was to assess the clinical significance of prolactin level obta...

A 43 year old Somali woman presented with increasing fatigue, difficulty getting out of her chair and 15 kg weight gain over a one month. Past medical history included paranoid psychosis, nasal congestion due to adenotonsillarhypertrophy, and human immunodeficiency virus (HIV). Her HIV infection was well controlled (viral load <50RNA copies/ml), with excellent immunological reconstitution (CD4 count >500 cells/mm3). Current medicat...