Searchable abstracts of presentations at key conferences in endocrinology

ea0014p270 | (1) | ECE2007

Tilapia GnRH receptors: signal transduction and internalization rate

Avitan Ayelet , Levavi-Sivan Berta

Multiple subtypes of GnRH receptor (GnRHR) are present in individual vertebrate species. We found two distinct GnRHRs in tilapia, classified as type 1 and 3 (tGnRHR1/3). Amino-acid similarity between the receptors was calculated at 59%, with the different amino acids scattered throughout the receptors. We compared the sequence analysis and signal transduction of the two tGnRHRs, using the human GnRHR type 1 as a control. Sequence analysis revealed that all three receptors exhi...