Endocrine Abstracts

Background: Patients with diabetes mellitus (DM) have been reported to have longer duration of in-hospital stay (DS). Identifying factors influencing their DS may help in the decision-making process especially in a public health setting.Aim: We aim to compare DS in patients with and without DM admitted to a medical unit in a university hospital and to determine the predictive factors of DS in patients with DM.Methods: A cross secti...

Introduction: SGLT2 (sodium-glucose cotransporter 2) inhibitors are a molecule more and more used in type 2 diabetes. However, it can cause a metabolic decompensation in some cases. Euglycemic ketoacidosis may be atypical, misplacing and delaying the diagnosis. We investigated the precipitating factors of this metabolic complication in our case study and in the literature.Presentation of the Case: We report the case of a normal BMI (19 kg/m2) ...

Objective: To describe the phenotypic and molecular characteristics of familial thyroid dyshormonogenesis (FTDH) in the Tunisian population.Patients and Methods: A retrospective descriptive study including two related (R and K) with high consanguinity whose members are carriers of FTDH. Biological and genetic screening was proposed for all consenting members.Results: FTDH was identified in 11 patients (8 girls, 3 boys) with a mean ...

Introduction: The solitary fibrous tumor is a rare spindle cell neoplasm, originally described in the pleural cavity. However, it can occur in other locations. Multiple primary cancers are a rare entity and their incidence is described at 5.5%. We report a case associating three neoplasms: a renal cell carcinoma, a mediastinal solitary fibrous tumor and a papillary thyroid cancer.Obervation: We report the case of a 38 year old patient with no particular ...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting women of reproductive age. PCOS has two phenotypes, obese and lean, the latter being a much less common presentation of the syndrome.Aim: Compare PCOS outcomes in patients with obese PCOS and patients with lean PCOS.Methods: A retrospective, single-center, descriptive and comparative study including patients with PCOS followed at the endocrinology d...

Introduction: Congenital Hypothyroidism is the principal cause of preventable mental retardation. It is due to Thyroid dysgenesis in 85% of the cases and in 15% to thyroid dyshormonogenesis.Methods: We conducted a prospective study including 17 patients with familial congenital hypothyroidism due to thyroid dyshormonogenesis other than the features of thyroid gland by ultrasound. Other than the phenotype we evaluated the functionality by thyroid Scintigr...

Introduction: Thyroid dyshormonogenesis represents 15% of congenital hypothyroidism. It is a genetic disorder due to a trouble of Thyroid hormones synthesis. it implies many factors involved in this process mainly TPO Enzyme and NIS channel.Methods: We conducted a prospective study including 17 patients with Congenital Hypothyroidism belonging to 4 consanguine multigenerational Tunisian families. The thyroid dyshormonogenesis was diagnosed based on clini...