Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep124 | Bone and Calcium | ECE2020

«Angio Scan-01» for extraskeletal calcification assessment in patients with mineral and bone disorders in chronic kidney disease

Maganeva Irina , Volodicheva Victoria , Eremkina Anna , Aynetdinova Alina , Mokrysheva Natalia

Background: Mineral and bone disorders in chronic kidney disease (CKD-MBD) is a systemic disorder of mineral metabolism due to CKD, which is manifestedby abnormalities of calcium, phosphorus, parathormone (PTH) and vitamin D; renal osteodystrophy; extraskeletal calcification. In patients with CKD, vascular calcification occurs 10–20 years earlier than in the general population, and is highly prevalent (40–92%) in the hemodialysis population. «AngioScan-01&#187...

ea0073yi12 | Young Investigator Awards | ECE2021

Preoperative predictors and prognostic factors of recurrence of the parathyroid carcinoma – Data of a multi-center study

Krupinova Julia , Voronkova Iya , Aynetdinova Alina , Pigarova Ekaterina , Mokrysheva Natalia

BackgroundThere are no specific markers for parathyroid carcinoma (PC) therefore, the development of algorithms for identifying high-risk patients is an urgent task.AimsTo determine clinical and laboratory predictors of PC and identify the factors of a poor prognosis.Materials and methodsA multi-center retrospective study included 242 patients with primary hyperpa...

ea0073aep124 | Calcium and Bone | ECE2021

The natural history of hypoparathyroidism according to the database of endocrinology research centre

Kovaleva Elena , Eremkina Anna , Aynetdinova Alina , Mokrysheva Natalia

BackgroundHypoparathyroidism is a rare disorder characterized by hypocalcemia and hyperphosphatemia due to absent or inadequate parathyroid hormone secretion. Data on effective treatment strategies and predictors of long-term complications have only recently began to emerge. The epidemiological information regarding chronic hypoparathyroidism in Russia is strictly limited that prompted this research.AimsTo es...

ea0073aep139 | Calcium and Bone | ECE2021

Metabolic disorders in patients with primary hyperparathyroidism

Bibik Ekaterina , Dobreva Ekaterina , Eremkina Anna , Aynetdinova Alina , Mokrysheva Natalya

BackgroundThe nonclassical complications of primary hyperparathyroidism (PHPT) can include metabolic syndrome associated with cardiovascular diseases. According to clinical studies, an increased incidence of diabetes mellitus, insulin resistance, obesity, dyslipidemia and other disorders are observed in patients with PHPT regardless of the severity of the disease. The aim of this study is to estimate metabolic parameters in patients with PHPT compared to...

ea0073ep22 | Calcium and Bone | ECE2021

Deficiency or insufficiency of vitamin D and the frequency of hypocalcemia episodes and the circadian rhythm of serum calcium level

Kovaleva Elena , Eremkina Anna , Aynetdinova Alina , Mokrysheva Natalia

IntroductionVitamin D deficiency is considered as a major public health concern. Due to vitamin D’s crucial role in the intestinal calcium absorption, its deficiency may result in hypocalcemia and in a spectrum of associated clinical manifestations.AimTo assess the effect of 25(OH) vitamin D level (25(OH)D) on the frequency of hypocalcemia episodes and the daily profile of serum calcium and 24-h urinary ...

ea0070aep164 | Bone and Calcium | ECE2020

Increasing incidence of parathyroid carcinoma according to russian registry of the primary hyperparathyroidism

Krupinova Julia , Veretennikova Julia , Maganeva Irina , Eremkina Anna , Aynetdinova Alina , Mirnaya Svetlana , Mokrysheva Natalia

Introduction: Parathyroid carcinoma (PC) occurs in 0.005% of all malignant tumors and in less than 1% in primary hyperparathyroidism (PHPT), but recent reports indicate increasing incidence of PC.Aim: To estimate the prevalence of PC in Russia and to identify its distinctive characteristics relevant as preoperative markers.Material and methods: We conducted a retrospective study based on the online Russian Registry of 3061 patients...

ea0073aep101 | Calcium and Bone | ECE2021

Association of preoperative factors and postoperative hypocalcemia after parathyroidectomy for primary hyperparathyroidism

Aynetdinova Alina , Eremkina Anna , Olga Yu. Rebrova , Kovaleva Elena , Mokrysheva Natalia

BackgroundParathyroidectomy (PTE) is the basic treatment for symptomatic primary hyperparathyroidism (PHPT). It is also recommended for some asymptomatic patients. However, PTE can be followed by some complications such as postoperative hypocalcemia.AimTo evaluate association of demographic, clinical, laboratory factors, preoperative cholecalciferol supplementation and hypocalcemia after PTE in patients with ...

ea0073aep106 | Calcium and Bone | ECE2021

Mineral and bone disorders in patients after combined kidney-pancreas or kidney transplantation

Maganeva Irina , Larina Irina , Severina Anastasia , Aynetdinova Alina , Eremkina Anna , Shamkhalova Minara , Mokrysheva Natalia

BackgroundThe kidney or kidney-pancreas transplantation corrects many of the metabolic or biochemical abnormalities associated with chronic kidney disease (CKD); however, mineral bone disease (MBD) and cardiovascular pathology remain frequent in transplant recipients. This happens especially in patients who have long history of secondary hyperparathyroidism (SHPT), as well immunosuppressive therapy plays an important role in the progression of MBD.<p...

ea0073aep128 | Calcium and Bone | ECE2021

COVID-19 and impaired calcium metabolism upon admission to the hospital

Maganeva Irina , Eremkina Anna , Bibik Ekaterina , Gorbacheva Anna , Kovaleva Elena , Aynetdinova Alina , Mokrysheva Natalia

IntroductionThere is evidence of the interaction between the main parameters of calcium-phosphorus metabolism, vitamin D and the course of a new coronavirus infection. Moreover, hypocalcemia is one of the most frequent biochemical disorders and is associated with severity of the disease, increased likelihood of hospitalization, need for mechanical ventilation, and poor prognosis in COVID-19.ObjectiveTo estima...