ea0007s32 | Joint BES and EFES symposium: Neuroactive steroids: implications for disease and healthy ageing | BES2004
Garcia-Segura L
, Veiga S
, Mendez P
, Garcia-Ovejero D
, DonCarlos L
, Azcoitia I
Endogenous as well as exogenous androgens and oestrogen have neuroprotective properties. Oestrogen is formed locally in neural tissue from precursor androgens. In the brain, the expression of aromatase, the enzyme that catalyses the conversion of androgens to oestrogen, is restricted, under normal circumstances, to specific neuronal populations involved in neuroendocrine control and in the modulation of reproductive or sexually dimorphic behaviours. However, the expression of ...