Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1296 | Clinical Cases–Thyroid/Other | ECE2015

Radioguided excision of occult metastatic lesion in thyroid carcinoma: a safe technique for previously operated neck in two patients

Martins Teresa , Azevedo Teresa , Santos Jacinta , Rodrigues Fernando , Rovira Eugenia , Oliveira Sofia , Neto Joao , Neves Antonio , Gilde Patricia , Cruz Carlos

Introduction: Intraoperative identification of neck lesions in patients who have undergone previous neck surgery is particularly difficult, because of operative scarring and distorted anatomy. Radioguided occult lesion localisation (ROLL) involves the preoperative intratumoral ultrasound-guided injection of a radioactive tracer. In the present study, we investigated the efficacy of roll in two patients with papillary thyroid cancer (PTC) who underwent previous neck exploration...

ea0049ep106 | Adrenal medulla | ECE2017

Loss diagnosis of pheochromocytoma in the initial evaluation

Azevedo Teresa , Alves Marcia , Guimaraes Joana , Dantas Rosa , Balsa Ana Margarida , Inacio Isabel

Introduction: In most cases, adrenal masses are non-functioning adrenocortical adenomas. On ‘Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline’ published in 2016, the experts ‘suggest against repeated hormonal work-up in patients with a normal hormonal work-up at initial evaluation unless new clinical signs of endocrine activity appear or there is worsening of comorbidities’.C...

ea0032p163 | Calcium and Vitamin D metabolism | ECE2013

Postsurgical hypoparathyroidism with ‘normal’ PTH

Azevedo Teresa , Martins Teresa , Lemos Manuel , Cunha Nuno , Valido Frederico , Rodrigues Fernando

Introduction: Hypoparathyroidism is characterized by hypocalcemia and low or inappropriately normal levels of PTH. The most common cause of hypoparathyroidism is iatrogenic due to anterior neck surgery. In recent years it was documented that vitamin D insufficiency is widespread.Aim: To investigate the cause of hypocalcemia in thyroidectomized patients with PTH within the reference range.Methods: Retrospective review of clinical re...

ea0032p1030 | Thyroid (non-cancer) | ECE2013

Radioiodine treatment of hyperthyroidism in the elderly

Azevedo Teresa , Martins Teresa , Neto Joao , Oliveira Sofia , Rovira Eugenia , Rodrigues Fernando

Introduction: Treatment of hyperthyroidism in older adults is crucial to reduce its morbidity and mortality. Radioactive iodine has been widely used in this age group due to its efficacy, safety and cost-effectiveness.Aim: To determine the efficacy of 131I for treatment of hyperthyroidism in the elderly.Methods: Retrospective study of 86 hyperthyroid patients aged ≥65 years who performed radioiodine therapy. We eva...

ea0022p835 | Thyroid | ECE2010

Hypothyroidism related to tyrosine kinase inhibitors: an underdiagnosed disorder?

Azevedo Teresa , Martinho Mariana , Martins Teresa , Dias Florbela , Cunha Nuno , Valido Frederico , Gervasio Helena , Rodrigues Fernando

Introduction: Tyrosine Kinase Inhibitors (TKIs) are approved for the treatment of several cancers and can induce hypothyroidism by unclarified mechanisms.Objectives: To assess the prevalence of hypothyroidism in patients treated with TKIs.Methods: Retrospective review of clinical records of patients treated with TKIs in our institution between 2003 and 2009. We evaluated parameters such as sex, oncologic pathology, TKI used, TSH an...

ea0022p836 | Thyroid | ECE2010

Procalcitonin: a promising role in medullary thyroid carcinoma?

Azevedo Teresa , Martinho Mariana , Martins Teresa , Cunha Nuno , Valido Frederico , Rodrigues Fernando

Introduction: Procalcitonin (PCT) is currently used as a sepsis marker. Studies have shown that this prohormone is elevated in patients with medullary thyroid carcinoma (MTC) and, additionally, that its assay could have less limitation than calcitonin (CT).Objective: To evaluate the concordance between the values of CT and PCT.Methods: CT, PCT and carcinoembryonic antigen (CEA) were measured in a total of 57 subjects. CEA and CT we...

ea0063p906 | Diabetes, Obesity and Metabolism 3 | ECE2019

Gestational Diabetes in Early Pregnancy – what does fasting glucose tell us?

Rosinha Patricia , Dantas Rosa , Alves Marcia , Azevedo Teresa , Inacio Isabel , Ferreira Sara Esteves , Pedrosa Carla , Albuquerque Isabel , Garrett Ana Catarina , Guimaraes Joana

Introduction: The association of fasting glucose (FG) in early pregnancy (EP) with adverse outcomes for the mother and her offspring is well known, although the best cut-offs for diagnosis of Gestational Diabetes (GD) are not consensual.Objetive: Evaluate the impact of FG in EP in the management of pregnant women and obstetric and fetal outcomes.Methods: Retrospective cohort of pregnant women with GD diagnosed before 24 weeks of ge...

ea0063p910 | Diabetes, Obesity and Metabolism 3 | ECE2019

Gestational Diabetes: what to say about body mass index and outcomes? The influence of prepregnancy body mass index on obstetric and neonatal outcomes of women with gestational diabetes

Ferreira Sara Esteves , Rosinha Patricia , Inacio Isabel , Alves Marcia , Azevedo Teresa , Dantas Rosa , Pedrosa Carla , Ferreira Marilia , Albuquerque Isabel , Fonseca Catarina , Jesus Andreia , Guimaraes Joana

Introduction: Due to the growing prevalence of obesity, more women are overweight in early pregnancy, leading to adverse neonatal and obstetric outcomes.Objective: To evaluate the influence of maternal prepregnancy body mass index (BMI) on blood glucose levels at diagnosis of gestational diabetes (GD), obstetric and neonatal outcomes.Methods: Retrospective observational study including women with GD and singleton pregnancy, with fo...

ea0063p989 | Diabetes, Obesity and Metabolism 3 | ECE2019

Metformin and Vitamin B12 deficiency: evaluation of vitamin B12, homocysteine and methylmalonic acid levels in type 2 diabetics

Inacio Isabel , Azevedo Teresa , Alves Marcia , Dantas Rosa , Balsa Ana Margarida , Ferreira Sara , Rosinha Patricia , Gomes Fernanda , Fonseca Catarina , Garret Ana , Jesus Andreia , Guimaraes Joana

Introduction: The American Diabetes Association guideline states that the long-term use of metformin may be associated with biochemical vitamin B12 (B12) deficiency and periodic measurement should be considered, although isolated serum B12 measurement has low sensitivity and specificity. Homocysteine (Hcy) and methylmalonic acid (MMA) are more sensitive biomarkers, the latter being more specific.Objectives: To estimate B12 deficiency in type 2 diabetics ...

ea0070aep1034 | Hot topics (including COVID-19) | ECE2020

Characterization of dyslipidaemia and association of lipoprotein(A) plasma levels with metabolic control in young adults with type 1 diabetes

Inácio Isabel , Ferrreira Sara , Rosinha Patrícia , Azevedo Teresa , Alves Márcia , Dantas Rosa , Balsa Ana Margarida , Guimarães Joana

Introduction: The 2019 European Society of Cardiology/European Atherosclerosis Society lipid guidelines changed the cardiovascular risk categories and LDL-C goals, and suggests that lipoprotein(a) [Lp(a)] measurement should be considered at least once in adult person’s lifetime. Although young people with type 1 diabetes (T1DM) without major cardiovascular risk factors (CVRF) were previously considered to be at low or moderate risk, they are at least at moderate risk bas...