Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep963 | Pituitary - Clinical | ECE2017

Infundibular lesion presenting with central diabetes insipidus and hypogonadism

Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Bakiner Okan , Bozkirli Emre , Ertorer M Eda

Introduction: Pituitary stalk lesions fall into three categories: congenital and developmental (rathke cleft cyst, ectopic neurohypophysis), inflammatory and infectious (hypophysitis, sarcoidosis, tuberculosis), and neoplastic (Langerhans cell histiocytosis, germinoma, metastatic tumors). Herein, we report a case with infundibular lesion presenting with central diabetes insipidus and hypogonadism.Case report: A 27-years old woman was admitted to our clin...

ea0049ep969 | Pituitary - Clinical | ECE2017

A case with headache and pitosis: pituitary macroadenoma or ophtalmoplegic migraine?

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bakiner Okan , Bozkirli Emre , Ertorer Melek Eda

Case: A 28-year old man was admitted to our hospital with complaints of three days of severe headache, diplopia and ptosis of the right eye. He had pituitary macroadenoma and had been on cabergolin 0.25 mg/week for the last six months. At physical examination, he demonstrated ptosis and inability to move the right eye medially. Magnetic resonance imaging showed a 13×12 mm pituitary mass with suprasellar extension and hemorrhage. Visual field analysis was abnormal except t...

ea0041ep291 | Clinical case reports - Pituitary/Adrenal | ECE2016

Radiotherapy for nasopharyngeal carcinoma: a rare cause of hypopituitarism

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bozkirli Emre , Bakiner Okan , Ertorer Melek Eda

Introduction: Radiotherapy to the head and neck area is the standard therapy used for the treatment of nasopharyngeal carcinoma. Hypopituitarism is a well-known late complication of cranial radiotherapy. Although very rarely, it may be observed following radiotherapy to the head and neck area, as well.Case report: A 53-year-old man was referred to our endocrinology department for hyponatremia and low free thyroxine (T4) with normal thyroid- st...

ea0037ep76 | Adrenal cortex | ECE2015

Ectopic thyroid tissue in the adrenal gland: report of a case

Bozkirli Emre , Bakiner Okan , Belli Sedat , Kocer Emrah , Ulusan Serife , Reyhan Mehmet

Background: Ectopic thyroid tissue (ETT) can be explained as the localisation of thyroid parenchyma outside the orthotopic position of the thyroid gland. It can be more easily found in the tongue, neck, mediastinum, great vessels, heart and anywhere along Wölfler area, but presentation in the adrenal glands is absolutely very rare.Case: A 39-year-old woman was referred to our Endocrinology outpatient clinic with an incidental adrenal mass which was ...

ea0016p181 | Diabetes and cardiovascular diseases | ECE2008

The impact of family history of type 2 diabetes mellitus on insulin sensitivity in lean subjects with polycystic ovary syndrome

Bozkirli Emre , Ertorer M Eda , Bakiner Okan , Anaforoglu Inan , Tutuncu N Bascil , Demirag N Guvener

Objective: Polycystic ovary syndrome (PCOS) is a common endocrine disorder, characterized by hyperandrogenism and chronic anovulation. Hyperinsulinemia and insulin resistance are well-documented features of the disease. In obese PCOS patients, family history of type 2 diabetes mellitus (FH-DM) is shown to be related with a decrease in insulin sensitivity, however not much is known about lean PCOS cases. The aim of this study was to determine the relationship between FH-DM and ...

ea0016p684 | Thyroid | ECE2008

Anti-BIP levels on Hashimoto's thyroiditis

Asik Mehmet , Sahin Mustafa , Arikan Serap , Gursoy Alptekin , Ayturk Semra , Bakiner Okan , Tutuncu Neslihan Bascil

To asses the presence of antibodies to BIP/GRP78, which is a chaperon of endoplasmic reticulum and has immune modulating and antiapoptotic effects in Hashimoto’s thyroiditis.The study included 62 patients with autoimmune thyroiditis. Of these, 20 had euthyroid, 27 had subclinical hypothyroid, and 15 had hypothyroid Hashimato’s thyroiditis. A control group including 37 healthy patients also participated in the study.There ...

ea0014p124 | (1) | ECE2007

Influence of Lanreotide Autogel on insulin sensitivity among patients with acromegaly

Eda Ertorer Melek , Bakiner Okan , Anaforoglu Inan , Bozkirli Emre , Bascil Tutuncu Neslihan , Guvener Demirag Nilgun

There are limited data inquiring the relationship between somatostatin analogues and insulin sensitivity among acromegalic cases. This study was conducted to evaluate short-term effects of lanreotide autogel (LA), administered every 28 days by deep subcutaneous injection, on insulin sensitivity among acromegalic patients with pituitary tumors. Before and following six months of LA treatment, insulin resistance and beta-cell function were calculated by using homeostasis model a...

ea0056p371 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

A difficult synchronous diagnosis; Type 2 Diabetes and insulinoma

Sefa Bakiner Okan , Bozkirli Emre , Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Ertorer Melek Eda

Background: In the literature there are rare cases of patients with known Type 2 Diabetes Mellitus whom are diagnosed as insulinoma. However a synchronous diagnosis with insulinoma and diabetes for a patient presenting with hypoglycemia symptoms is not an expected condition.Case: A 79 years-old female patient was sent to our Endocrinology outpatient clinic because of repeating minor and major hypoglycemia attacks. She had no important finding in her back...

ea0056p372 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Immunoglobulin G4 related pancreatitis; can it be a rare cause of secondary diabetes?

Bozkirli Emre , Bakiner Okan Sefa , Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Ertorer Melek Eda

Background: Autoimmune pancreatitis (AIP) is a relatively new entity in which the exocrine pancreas shows lymphocytic infiltration. There are two subtypes of AIP; Type 1 related with Immunoglobulin G4 (IgG4) as the pancreatic manifestation of IgG4-related disease (IgG4-RD), and Type 2 related with granulocytic infiltration. The characteristic features of Type 1 AIP are increased serum IgG4 levels, lymphoplasmacytic sclerosing pancreatitis (infiltration of IgG4+ plasmacytes and...

ea0056p697 | Clinical case reports - Pituitary/Adrenal | ECE2018

Pasireotide a new option for acromegaly

Haydardedeoglu Filiz Eksi , Bakiner Okan , Bozkirli Emre , Bagir Gulay Simsek , Ertorer Melek Eda

Background: Acromegaly is a rare neuroendocrine disorder caused by secretion of excessive levels of growth hormone. Somatostatin receptor ligands (SRLs) are first-line medical therapies for patients in whom surgery has failed or is contraindicated. We report a case who had inadequate response to multiple therapies including surgery,radiotherapy,octreotide,lanreotide,cabergoline and pegvisomant.Case: An 44-year-old woman was admitted to our hospital with ...