ea0063p1123 | Reproductive Endocrinology 2 | ECE2019
Maseroli Elisa
, Cellai Ilaria
, Corno Chiara
, Rastrelli Giulia
, Filippi Sandra
, Comeglio Paolo
, Amoriello Roberta
, Ballerini Clara
, Sarchielli Erica
, Morelli Annamaria
, Maggi Mario
, Vignozzi Linda
Inflammation is hypothesized to play an important role in several diseases associated to the female genital tract and dihydrotestosterone (DHT) has shown immunomodulatory protective effects in experimental models of chronic inflammation. In the present study we aimed to evaluate the potential anti-inflammatory effects of DHT in a model of smooth muscle cells (hSMCs) isolated from human vagina biopsies and their potential role as APCs (Antigen Presenting Cells), crucial for the...