Endocrine Abstracts

Introduction: Pseudo-hypoparathyroidism (PHP) is a rare endocrine disorder characterized by resistance to parathyroid hormone (PTH). We present a case of a 33-year-old, focusing on the clinical presentation, diagnostic, and management strategies, with particular attention to skeletal manifestations and tissue calcifications.Case Description: The patient presented to the hospital with severe symptomatic hypocalcaemia. Ini...

Introduction: Regional Migratory Osteoporosis (RMO) is a rare condition, characterised by a self-limiting migratory arthralgia, which generally tends to involve the lower limbs. The arthralgia is usually, not associated with any history of trauma. Radiologically, Magnetic Resonance Imaging (MRI) is the investigation of choice. Bone Marrow Oedema (BMO) with subchondral sparing are the usual findings in patients with RMO. This condition is usually under diagnosed due to the comp...

Introduction: Waterhouse Friedrichsen syndrome-Severe adrenal insufficiency is a rare but life-threatening condition secondary to bilateral adrenal haemorrhages. In many cases, it is caused by fulminant meningococcaemia, but there are numerous other aetiologies, it can also be caused by use of medications that promote blood clotting, reduce platelet count, primary antiphospholipid syndrome, renal vein thrombosis or steroid use and has been associated with splenectomy as well. ...

We report a rare case of propylthiouracil (PTU) induced ANCA-associated-vasculitis (AAV). This young lady with recurrent thyrotoxicosis and positive Thyroid peroxidase and TSH receptor antibodies since 2004 was treated with Carbimazole but was changed to PTU 100 mg daily during pregnancy in 2012.She was admitted to our hospital in January 2015 with sore throat, feeling unwell and neutropenia 1.2 (normal range (NR): 1.6–7.5) 10×9/l. Thyroid func...

Case: An 89 year old gentleman was admitted to hospital following a collapse at home. His capillary blood glucose was found to be 1.4 mmol/l by the paramedics. The patient had experienced multiple collapses at home in the preceding 2 weeks. Each time, he had been found to be hypoglycaemic but treated and discharged from A&E. He complained of reduced appetite, weight loss and change in bowel habit. The patient’s past medical history included a large fibroma of the left...

Background: Lifelong surveillance should be offered to people with hereditary phaeochromocytoma and paraganglioma (PPGL), including asymptomatic carriers of pathogenic gene variants. Regular biochemical and radiological surveillance aims to improve disease detection and prognosis. During the COVID-19 pandemic, outpatient appointments were cancelled or postponed. Departments continue to face large backlogs of work. Clinicians in the USA reported 15% PPGL patients missing at lea...