Endocrine Abstracts

Background: A major challenge in the management of breast cancer (BC) is the search for biomarkers that are sensitive and less invasive. miRNAs are reported to be tissue-specific, stable and aberrantly expressed in different tumours, hence their emerging role as potential biomarkers in BC management.Objective: The study focused on developing an in-house method for the detection of mir-145 and mir-21 using SYBR Gre...

Background: A major challenge in the management of breast cancer (BC) is the search for biomarkers that are sensitive and less invasive. miRNAs are reported to be tissue-specific, stable and aberrantly expressed in different tumours, hence their emerging role as potential biomarkers in BC management.Objective: The study focused on developing an in-house method for the detection of mir-145 and mir-21 using SYBR Gre...

Recently there has been reports that the administration of hormonal contraceptives alter the metabolic processes and micronutrients levels. Meanwhile some of these micronutrients are cofactors and or coenzymes of enzymes and are involved in important metabolic pathways. We compared the influence of three contraceptive methods (oral contraceptive, injectables and implants) on serum levels of Iron, ferritin, copper, ceruloplasmin and Vitamin E, using standard methods. Blood samp...