ea0017oc6 | Endocrinology 2 | BSPED2008
Solomon M
, Renehan A
, Morjaria R
, Patel L
, Whatmore A
, Shaikh G
, Amin R
, Banerjee I
, Clayton P
Background: A polymorphism of the GHR gene, deletion of exon 3 (d3 GHR), has been associated with improved growth response to GH in some studies. We investigated the effect of this polymorphism across several diagnoses, evaluating parameters of growth outcome from a single institution (Manchester) and combined these with those derived from the literature using meta-analytical approaches.Methods: GHR genotype was assessed by PCR and related to clinical an...