Searchable abstracts of presentations at key conferences in endocrinology

ea0019s28 | The endoplasmic reticulum – an important link between inflammation, stress and metabolism | SFEBES2009

The endoplasmic reticulum as a metabolic compartment

Banhegyi G

The endoplasmic reticulum (ER) is a metabolic compartment participating in virtually all anabolic and catabolic branches of cellular metabolism. The redox balance of pyridine nucleotides is a major regulator of the metabolism. Several observations demonstrate their presence in the lumen of the ER. NADPH donates electrons for biosynthetic reactions, biotransformation and antioxidant defense; its reduced state is ensured by NADP+-dependent dehydrogenases. In the ER lu...