Searchable abstracts of presentations at key conferences in endocrinology

ea0055oc5 | National Clinical Cases | SFEEU2018

Stalk and infudibular thickening – A diagnostic conundrum

Banu Zeenat , Menon Ravi

Case history: Fifty-eight years old gentleman referred to endocrinology with erectile dysfunction and decreased libido for 1 year. He denied headache or visual disturbance. His past medical history include ulcerative colitis (1998), mild asthma, anterior scleritis (2003), previous DVT (1994), Episode of steroid induced psychosis in past. He is on levothyroxine, sulfasalazine, calcium /vitamin D and long term prednisolone 4 mg (9 years). Examination reveal testicular volume of ...

ea0044ep18 | (1) | SFEBES2016

Bilateral adrenal nodules and phaeochromocytoma associated with neurofibromatosis

Banu Zeenat , Menon Ravi

We report two cases of unilateral and bilateral phaeochromocytoma in patients with neurofibromatosis type 1 (NF-1) respectively.Case 1 64 year old Caucasian male with known NF-1, hypertension, depression and osteoarthritis was referred with episodic symptoms of palpitation, chest pain and breathlessness. Biochemically confirmed phaeochromocytoma with 24 hr urinary metanephrines of 18595 nmol/24 hrs. CT revealed 4.2 cm right adrenal...

ea0041ep284 | Clinical case reports - Pituitary/Adrenal | ECE2016

Isolated hypoprolactinaemia: two cases

Banu Zeenat , Menon Ravi

Case 1: 38 year old was referred for sub-fertility. She had one normal childbirth 5 years ago. There was failure to lactate following the childbirth. There was some puerperal blood loss, but she resumed normal menstrual periods and had no other manifestations of hypopituitarism. Pituitary profile showed normal results FSH 2.7 IU/l; LH 1.5 IU/l; 0900 h cortisol 305 nmol/l/l/ TSH 2.85 μ/l. Prolactin was 85 μ/l. IGF1 18.6 nmol/l. Short synacthen was normal. Previous MRI...

ea0038p420 | Steroids | SFEBES2015

Phaeochromocytoma related reversible Takotsubo cardiomyopathy

Banu Zeenat , Chong Patrick

Stress related cardiomyopathy or Takotsubo LV dysfunction has been described in phaeochromocytoma related cardiomyopathy.16 y female, admitted in A&E on 23 June 2013 with severe epigastric pain, vomiting and dyspnoea. History of episodes of palpitations and exertional syncopal attacks for 2 years, for which she had been investigated. Her symptoms were attributed to panic attacks. There was no known family history of Endocrinopathy. On admission, BP w...

ea0038p427 | Steroids | SFEBES2015

Cushing’s syndrome secondary to bilateral functioning adrenocortical adenoma

Banu Zeenat , Kassim Saiful

Sixty seven years old lady was admitted with profound weakness and weight loss for 3–4 months. She has background of Primary hyperparathyroidism, HTN and Osteoporosis.Examination revealed BP of 175/90 mmHg, slightly plethoric with proximal myopathy and bruising. CTTAP bilateral axillary and para aortic lymphadenopathy and right adrenal adenoma 32×26 mm. CT guided biopsy which showed CLL. She was worked up f...

ea0055p07 | Poster Presentations | SFEEU2018

A rare case of Buprenorphine patch induced central adrenal insufficiency

Chok Yin Ling , Banu Zeenat , Gannon David

Case history: A 39-year-old lady first presented to our endocrine outpatient clinic in September 2014 when blood tests at her GP surgery showed serum cortisol of 65 nmol/l. She had been having chronic back pain which is treated with Buprenorphine patches for many years. A Short Synacthen test (SST) showed an inadequate response. A low ACTH suggest secondary adrenal insufficiency. Other pituitary function tests and MRI of the pituitary were normal. After staying off buprenorphi...

ea0065p415 | Thyroid | SFEBES2019

Thyroid dysfunction in adult hematopoietic stem cell transplant patients treated with Alemtuzumab based conditioning

Banu Zeenat , Hockings Catherine , Simpson Helen

Objective: To study the effect of alemtuzumab used in Reduced Intensity Conditioning prior to hematopoietic stem cell transplant (HSCT) on thyroid function.Methods: This retrospective case review of 13 patients (9 male, 4 female) who underwent HSCT and had alemtuzumab based conditioning regimen. 5 patients had Acute lymphoblastic leukaemia, 3 severe a plastic anaemia, 1 acute myeloid leukaemia, 1 congenital bone marrow failure, 1 chronic granulomatous di...

ea0062p71 | Poster Presentations | EU2019

Late effects of cancer treatment: it’s not always the pituitary

Banu Zeenat , Grandage Victoria , Simpson Helen

A 21 years old male, diagnosed with ALL in 2003 (aged 9), completed treatment in June 2009 (aged 15). Chemotherapeutic agents included doxorubicin, daunorubicin, cytarabine, mercaptopurine, methotrexate, asparaginase, vincristine, dexamethasone (7 mg for 3.5 years). He didn’t receive any cranial irradiation. He underwent endocrine assessment aged 15 because of delayed puberty and had testosterone replacement for 4 years (September 2012 till January 2016). He also had hist...

ea0069p63 | Poster Presentations | SFENCC2020

Coexistence of Refetoff syndrome and papillary thyroid carcinoma

Aziz Umaira , Banu Zeenat , Eltayeb Randa , Eldigair Hiba , Yousseif Ahmed , Karra Efthimia

A 30 year-old Caucasian male presented for a routine check-up. He was known to have abnormal thyroid function tests since the age of 23 years of unclear nature/aetiology. He reported occasional palpitations and anxiety. There were no other symptoms on systems’ review. He did not take regular medication, was an ex-smoker and consumed alcohol socially. His mother had hypothyroidism and his maternal aunt’s thyroid nodules. He was euthyroid. A palpable isthmic nodule &#7...

ea0069p68 | Poster Presentations | SFENCC2020

Refractory cyclical cushing’s – clinical challenges

Banu Zeenat , Eltayeb Randa , Aziz Umaira , Eldigair Hiba , Tickle Eliane , Khoo Bernard , Yousseif Ahmed , Al-barazi Sinan , Karra Efthimia

Case history: Cyclical Cushing’s is a very rare disease with rhythmic fluctuations in cortisol production with or without phenotypic features. It is a very challenging entity to diagnose. The low index of clinical suspicion is key for timely diagnosis and prevention of long-term complications. A 66 years old male presented with intermittent, episodic bilateral leg swelling and reversible weight gain of ˜6 kg following these episodes. Background history entailed femor...