Searchable abstracts of presentations at key conferences in endocrinology

ea0003p199 | Neuroendocrinology | BES2002

Serum IGF-I levels and correlation with functional activity in the elderly

Jenkins P , Barber M , Camacho-Hubner C , Braid V , Gilmore D , Stott D

Introduction: Ageing is associated with a decrease in activity of the growth hormone / IGF-1 axis. However, there is little normative data for serum IGF-I levels in the very elderly and the relationship of IGF-1 levels to muscle function and physical performance in geriatric inpatients has not been fully explored. We studied elderly patients rehabilitating after proximal femoral fracture (PFF), hypothesising that patients with lower circulating IGF-1 levels would have poorer p...

ea0005p3 | Bone | BES2003

Functional and association studies of calcium sensing receptor polymorphisms and mediators of calcium homeostasis

Harding B , Curley A , Christie P , Bowl M , Turner J , Barber M , Hampson G , Spector T , Thakker R

The calcium sensing receptor (CaSR) plays a central role in altering the secretion of parathyroid hormone (PTH) in response to alterations in extracellular calcium, and four studies have reported an association between CaSR polymorphisms and serum Ca 2+, serum PTH, and bone mineral density (BMD). However, two other studies have failed to detect such associations. We have therefore undertaken studies to investigate the Ala986Ser, Arg990Gly, and Gln1011Glu CaSR polymo...

ea0099p61 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Evaluation of the digital support tool gro health W8Buddy as part of tier 3 weight management service

Abdelhameed Farah , Hanson Petra , Sahir Mohammed , Parsons Nick , Panesar Arjun , de la Fosse Michaela , Summers Charlotte , Kaura Amit , Randeva Harpal , M Barber Thomas

Introduction: The escalating prevalence of obesity worldwide increases the risk of chronic diseases and diminishes life expectancy with growing economic burden necessitating intervention. The existing tiered approach to weight management, particularly specialist Tier 3 services, falls short of meeting the population’s needs. The emergence of digital health tools, while promising, lacks exploration in specialized NHS weight management services (WMS)....