Searchable abstracts of presentations at key conferences in endocrinology

ea0008p8 | Clinical case reports | SFE2004

A sweet case of refractory hypokalaemia

Barber TM , Chapman AJ

Apparent Mineralocorticoid Excess (AME) resulting from liquorice ingestion is rare. Liquorice is still popular, however, and must be considered in the differential diagnosis of patients presenting with hypertension and hypokalaemia.A 62 year-old woman presented with refractory hypertension (blood pressure 200/118 mmHg) and hypokalaemic alkalosis (serum K 2.98 millimoles per litre; bicarbonate 30 millimoles per litre). There was no sign of Cushing's Syndr...

ea0019p92 | Clinical practice/governance and case reports | SFEBES2009

A case of mistaken identity: metastatic thyroid follicular carcinoma masquerading as an incidental solitary pulmonary carcinoid lesion

Barber TM , Herbert A , Wingfield-Digby E , ElSheikh M , Simpson H , Marks N

We present a fascinating and instructive case of unexplained suppression of thyroglobulin (Tg) levels following resection of a presumed carcinoid tumour, subsequent re-examination of which revealed it to be a solitary metastasis from a follicular thyroid carcinoma.The patient, RB is a 79-year-old woman who presented 11 years ago with a 2-week history of neck swelling. Examination revealed a 5 cm diameter nodule in the left lobe of the thyroid, confirmed ...

ea0011p693 | Reproduction | ECE2006

Association between polymorphisms within the SUR1/Kir6.2 gene region and polycystic ovary syndrome: a case-control study

Barber TM , Zeggini E , Goh MJ , Webber L , Wass JAH , Franks S , McCarthy MI

Hyperinsulinaemia has an important role in the aetiology of Polycystic Ovary Syndrome (PCOS). Logical candidate genes for the development of PCOS therefore include those genes that influence β-cell insulin secretion such as ABCC8 and KCNJ11 on human chromosome 11. These two genes encode the SUR1 and kir6.2 components of the β-cell kATP channel respectively. To our knowledge, these genes have not been studied in women with PCOS previously.<p class="a...

ea0031p212 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

The public distress domain of quality of life correlates directly and independently with BMI in pre-operative morbidly obese patients awaiting metabolic surgery

Aftab Syed Abdus Saboor , Reddy N , Piya MK , Fraser I , Menon V , Bridgwater S , halder L , Kendrick D , Kumar S , Barber TM

Background: There is uncertainty regarding the selection of obese patients for metabolic procedures, how to define a successful outcome and pre-operative predictors of success. Our aim was to explore the influence of obesity on preoperative quality of life in patients awaiting bariatric surgery.Methods: Pre-operative data were accrued for morbidly obese patients (n=70) at the University Hospitals Coventry and Warwickshire (UHCW) during the last ...

ea0031p239 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

Preoperative characteristics of morbidly obese patients who achieved at least 50% excess weight loss post-metabolic Surgery

Aftab Syed Abdus Saboor , Reddy N , Piya MK , Fraser I , Menon V , Bridgwater S , Halder L , Kendrick D , Kumar S , Barber TM

Background: Pre-operative predictive measures of post-metabolic surgery success would facilitate a more refined evidence-based selection of patients. This study aimed at identifying those clinical and psycho-social predictors of success (defined as weight-loss) following metabolic surgery.Methods: Pre-operative data including IWQOL-Lite questionnaire (a validated self-reported 31-item measure of physical function, self-esteem, sexual life, public distres...