Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1472 | Thyroid (non-cancer) | ECE2017

Birt–Hogg–Dubé and papillary thyroid carcinoma: a case report

Barka Ines , Krompa Katherina , Baudry Camille , Caux Frederic , Bihan Helene

Background: Birt–Hogg–Dubé (BHD) syndrome has been reported to be associated with neoplastic conditions. Its association with thyroid carcinoma has been reported but remains controversial. Here we report the case of a BHD patient with a thyroid papillary carcinoma.Case report: A 47-year-old man presented with asymptomatic facial papules, which had been gradually increasing in number for 6 years. A biopsy was taken from a papule on the nose...

ea0041ep407 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

A rare form of pancreatic diabetes: a 25 year-follow-up

Cheikhrouhou Nesrine , Barka Ines , Elleuch Koussay , Slim Ines , Chaieb Larbi

Introduction: Fibrocalculous pancreatic diabetes is an uncommon type of diabetes mellitus due to chronic calcific non-alcoholic pancreatitis. It is associated to several particularities based on glycemic control and the occurrence of degenerative and metabolic complications, in addition to chronic pancreatitis complications.Observation: A 17-year-old male, with no familial history of diabetes and no alcohol consumption, was hospitalized in 1989 for keton...

ea0049ep441 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Diabetic nephropathy in type 1 diabetes mellitus

Barka Ines , Chikhrouhou Nesrine , Maaroufi Amel , Kacem Maha , Chaieb Molka , Ach Koussay

Nephropathy is a serious complication of Type 1 diabetes mellitus (T1DM) with a grave prognosis after the onset of proteinuria. End stage of renal disease remains the major cause of excess morbidity and premature mortality in patients with T1DM. The aims of the present study were to investigate the prevalence of diabetic nephropathy and to evaluate risk factors for its development among patients developing T1 DM. Seventy six patients with T1DM history over 20 years were includ...

ea0049ep1389 | Thyroid (non-cancer) | ECE2017

Cytohistologic correlation of thyroid nodules

Barka Ines , Ouerdani Senda , Chaieb Molka , Ben Abdelkrim Asma , Maaroufi Amel , Kacem Maha , Ach Koussay

Background: The discovery of a thyroid nodule exposes the problem of the possibility of thyroid cancer. The difficulty of management of this situation is the fact that only the histopathological examination can confirm or refute the malignancy. Fine-needle aspiration (FNA) is used as a diagnostic tool to assess thyroid nodules. The purpose of our study is to correlate the clinical, ultasonographic, the FNA results and final pathology to determine the predictors of malignancy o...

ea0041ep306 | Clinical case reports - Pituitary/Adrenal | ECE2016

Visual impairment revealing a growth hormone-producing pituitary adenoma in an 14-year-old boy: a case report

Barka Ines , Dendena Emna , Hasni Yosra , Maaroufi Amel , Kacem Maha , Chadli Molka , Ach Koussay

Background: Gigantism indicates excessive secretion of growth hormone (GH) during childhood Pituitary gigantism is very rare and the description of the disease is limited to small series and case reports. Here, we report a case of pituitary gigantism in a child revealed with visual defect.Case report: A 14-year-old boy presented with headache and left visual loss. On examination, he had visual acuity in his right eye of 2/10. His height was 178.0 cm (3 c...

ea0041ep978 | Thyroid (non-cancer) | ECE2016

Factors associated with persistent atrial fibrillation after achievement of euthyroid state

Melki Amel , Yazidi Meriem , Barka Ines , Chaker Fatma , Chihaoui Melika , Rjeb Ons , Slimane Hedia

Introduction: Atrial fibrillation (AF) occurs in up to 15% of patients with hyperthyroidism. Although hyperthyroidism is usually regarded as a reversible cause of AF, spontaneous sinus conversion occurs in only 2/3 of patients upon the normalization of T4 levels. The aim of this study was to identify factors associated with persistent atrial fibrillation after restoration of euthyroid state.Methods: We conducted a retrospective study of 13 years. Twenty ...

ea0041ep999 | Thyroid (non-cancer) | ECE2016

Risk Factors for the development of hypothyroidism after thyroid lobectomy

Barka Ines , Chaker Fatma , Bouzouita Hajer , Chihaoui Melika , Kilani Osman , Yazidi Mariem , Rejeb Ons , Slimane Hedia

Bakground: Thyroid-lobectomy is a frequent procedure performed in patients with a variety of thyroid conditions.The aim of this study is to determine the prevalence of post-operative hypothyroidism and the risk factors of hypothyroidism in patients undergoing thyroid-lobectomy.Patients and methods: We retrospectively reviewed patients who underwent a thyroid lobectomy for benign disease from january 2000 to 2014. Patients with known hypothyroidism before...

ea0041ep1059 | Thyroid (non-cancer) | ECE2016

Hoffmann syndrome: a case report

Barka Ines , Maaroufi Amel , Badr Wafa , Hasni Yosra , Kacem Maha , Chadli Chaieb Molka , Ach Koussay

Background: Hoffmann syndrome is a rare form of hypothyroid myopathy in adults characterized by presence of muscle weakness, stiffness and pseudo-hypertrophy. Here, we report a case of Hoffman syndrome aggravated by statin therapy.Case report: We describe the case of a 60 year old woman with primary hypothyroidism who presented with fatigue, cold intolerance, constipation, exertional breathlessness, progressive proximal muscle weakness and swelling of th...

ea0056p765 | Neuroendocrinology | ECE2018

Rathke’s cleft cyst mimiking pituitary apoplexy: a case report

Barka Ines , Bensmaine Faiza , Bah Moctar , Bouche Clara , Gautier Jean Francois

Introduction: The most common sellar lesions are mainly due to pituitary adenomas, craniopharyngiomas and benign cysts. Rathke’s cleft cyst (RCC) is a developmental sellar or suprasellar cystic lesion, which rarely becomes symptomatic. Here, we present an interesting case of intra sellar RCC, with a presenting feature of acute pituitary apoplexy.Case report: A 39 year old healthy women was referred to the emergency room for sudden headache and fatig...

ea0063p228 | Pituitary and Neuroendocrinology 1 | ECE2019

Long terms effects of cranial irradiation for nasopharyngeal carcinoma on hypothalamic-pituitary function – a 5-years longitudinal study

Taieb Ach , Ines Barka , Asma Ben Abdelkrim , Yosra Hasni , Amel Maaroufi , Maha Kacem , Molka Chaieb , Koussay Ach

Introduction: Pituitary insufficiency is a late-onset sequel of cranial irradiation for nasopharyngeal tumors. In a Cancer Survivor Study, 43% of patients treated for nasopharyngeal tumors had one or more endocrinopathies. We aim to characterize the pituitary-related outcomes following cranial radiotherapy for nasopharyngeal tumors over a period of 5 years.Material and methods: The effects of cranial irradiation on hypothalamic-pituitary function were st...