ea0070aep675 | Pituitary and Neuroendocrinology | ECE2020
Martel-Duguech Luciana
, Alonso-Pérez Jorge
, Bascuñana Helena
, Diaz-Manera Jordi
, Alonso-Jimenez Alicia
, Llauger Jaume
, Nuñez-Peralta Claudia
, Montesinos Paula
, Webb Susan M.
, Valassi Elena
Background: Muscle weakness persists in patients with acromegaly (ACRO) even long-term after disease control. Mechanisms determining this sustained impairment are not known. We hypothesized that alteration of muscle architecture, due to intramuscular fatty infiltration, is associated with muscle dysfunction in these patients.Patients and Methods: Thirty-seven acromegalic patients [21 females and 16 males, mean (± s.d.)age, 53 ± 9 years...