Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep843 | Reproductive and Developmental Endocrinology | ECE2020

Hyperandrogenism in a postmenopausal woman secondary to an androgen secreting steroid cell tumor of the ovary

Bastos Filipa , Franco Sara , Ferreira Ana , Manita Isabel , Portugal Jorge

Introduction: Androgen secreting neoplasms of the ovary are rare and usually show autonomous secretion. Steroid cell tumors of the ovary represent less than 0.1% of all ovarian tumors and are a subgroup of sex cord-stromal tumors. In most cases, patients present with androgenic clinical features.Case report: A 58-year-old woman complained of rapid onset of androgenic alopecia, excessive hirsutism and clitoromegaly. Endocrine assessment showed high levels...

ea0055wa13 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Cushing’s disease relapse associated with central diabetes insipidus

Ferreira Ana , Silva Tiago , Bastos Filipa , Manita Isabel , Cordeiro Maria Carlos , Portugal Jorge

Introduction: Central diabetes insipidus (DI) is a frequent complication of transfenoidal surgery for Cushing’s disease (CD). It can be transient or, more infrequently, permanent. The most common mechanism results from surgical neurohypophyseal damage rather than local mass effect from the pituitary adenoma.Case report: A 40 years old woman was referred to our Endocrinology outpatient clinic at the beginning of 2015 for new onset hypertension, signi...

ea0063p1076 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma – is there a relationship between T2W signal intensity in MRI and response to treatment with dopamine agonists?

Ferreira Ana , Oliveira Guilherme , Bastos Filipa , Carlos Cordeiro Maria , Duarte Julia , Portugal Jorge

Introduction: Prolactinomas are mostly benign tumours usually managed with pharmacological treatment. Some, however, seem to be resistant to dopamine agonists (DA) for unclear reasons. The relationship between T2W signal intensity (T2WSI) and response to treatment with somatostatin analogs is well described in acromegaly patients. Some evidence suggests that prolactinoma’s T2W hypointensity might be related to higher baseline prolactin levels and more resistance to DA.</p...

ea0063p1081 | Pituitary and Neuroendocrinology 3 | ECE2019

ACTH-positive diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH)

Ferreira Ana , Bastos Filipa , Pedro Paula , Lopes Miguel , Carlos Cordeiro Maria , Portugal Jorge

Introduction: DIPNECH is a preinvasive condition in which there is an idiopathic generalised proliferation of pulmonary neuroendocrine cells that can form tumourlets. There are very few cases described of ACTH secretion by these cells causing Cushing’s syndrome, some of them cyclic.Case report: A 41 year-old woman was sent to our Endocrinology outpatient clinic for menstrual disturbance, acne and excessive sweating. She had a recent diagnosis of DIP...

ea0063p990 | Diabetes, Obesity and Metabolism 3 | ECE2019

What is the factor that most influences perinatal outcomes in pregnant women with Gestational Diabetes Mellitus: Country of origin or previous Gestational Diabetes?

Ferrinho Catia , Matos Ana Catarina , Cordeiro Maria Carlos , Bastos Filipa , Ferreira Rute , Duarte Joao Sequeira , Oliveira Manuela , Portugal Jorge

Introduction: Gestational Diabetes Mellitus (GDM) is one of the pregnancy diseases with the highest rate of complications, influenced by several factors. Its prevalence has increased, with a prevalence of 7.2% in Portugal.Objective: Characterize pregnant women with GDM and evaluate the perinatal outcomes according to the country of origin and previous GDM.Material and methods: Cross-sectional and retrospective study. We collected c...

ea0070aep721 | Pituitary and Neuroendocrinology | ECE2020

Septo-optic dysplasia with late-onset diagnosis: An uncommon presentation of a rare disease

Duarte Vitória , Ivo Catarina , Veríssimo David , Franco Sara , Bastos Filipa , Marcelino Mafalda , Vara Luiz Henrique , Portugal Jorge

Background: Septo-optic dysplasia (SOD), also known as de-Morsier syndrome, is a rare congenital disorder characterized by any combination of optic nerve hypoplasia, pituitary dysfunction and midline abnormalities of the brain. Clinical diagnosis requires the presence of at least two of the features. This disorder is equally prevalent in males and females, with a reported incidence of 1/10,000 live births. There is wide variation in the severity of the clinical features found....

ea0070ep269 | Endocrine-related Cancer | ECE2020

Multiple endocrine neoplasia: A case series of 7 families

Duarte Vitória , Ivo Catarina , Veríssimo David , Marcelino Mafalda , Vara Luiz Henrique , Franco Sara , Bastos Filipa , Manita Isabel , Raimundo Luisa , Portugal Jorge

Introduction: Multiple endocrine neoplasia (MEN) is a rare genetic syndrome characterized by occurrence of tumors involving two or more endocrine glands. Four types are described: MEN1, MEN2, MEN3 and the recently identi&#-1279;ed MEN4. Due to the complexity of the syndromes, it is difficult to manage these patients. Our objective was to describe the clinical features of individuals from 7 families with a diagnosis of MEN1 or MEN2 and identify current challenges in clinical pr...

ea0073aep311 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Impact of the COVID pandemic and lockdown in the glycemic and weight control of patients with type 1 and type 2 diabetes – data from a Portuguese hospital

Franco Sara , Bastos Filipa C. , Ana Gonçalves Ferreira , Barbosa David , Ricardo Capitão , Costa Maria Manuel , Luiz Henrique Vara , Manita Isabel , Cordeiro Maria Carlos , Luísa Raimundo , Portugal Jorge

IntroductionDue to the COVID pandemic, Portugal was forced to start lockdown on March 18 th that lasted until June 1st. Lockdown caused a lot of changes in the daily activities of the Portuguese people, such as eating habits, exercise, time spent at home and stress management. After the lockdown people noticed difficult access to healthcare.ObjectiveOur aim was to evaluate if these changes had an i...