Searchable abstracts of presentations at key conferences in endocrinology

ea0077p86 | Neuroendocrinology and Pituitary | SFEBES2021

A rare case of sellar pathology: Coinciding IgG4-related hypophysitis and pituitary adenoma

Hakami Osamah , Fountas Athanasios , Chavda Swarupsinh , Tsermoulas George , Ayuk John , Batra Ruchika , Karavitaki Niki

A 69-year-old man was referred to our Pituitary Service for a 3-month history of progressive right visual loss and a finding of “pituitary enlargement” on brain MRI. He reported erectile dysfunction and his medical history included asthma, DM2 and meningitis (8 years ago). Neuro-ophthalmology review showed visual acuity 6/60, optic neuropathy, marked visual field loss with residual superonasal island in right eye, mild 6th nerve palsy. Pituitary MRI: infil...

ea0077p91 | Neuroendocrinology and Pituitary | SFEBES2021

Rathke’s cleft cyst with a very unusual course

Coulden Amy , Pepper Joshua , Juszczak Agata , Batra Ruchika , Chavda Swarupsinh , Senthil Latha , Ayuk John , Pohl Ute , Nagaraju Santhos , Karavitaki Niki , Tsermoulas Georgios

A 31-year-old man without previous medical history presented to his local hospital with one week history of generalised severe headache. Brain CT was reported as negative for acute intracranial pathology. Five weeks later, he re-presented with worsening headache and blurring of vision. Brain CT revealed a large area of hypodensity centred on the left thalamus/basal ganglia and subsequent MRI with contrast showed a medium size pituitary cyst with suprasellar extension and two c...

ea0065p284 | Neuroendocrinology | SFEBES2019

Silent somatotroph pituitary neuroendocrine tumours (PitNETs): systematic review of cases from a Pituitary Centre

Nazir Muneer Ahmad Abdul , Fountas Athanasios , Lithgow Kirstie , Ayuk John , Toogood Andy , Gittoes Neil , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Nagaraju Santhosh , Pohl Ute , Karavitaki Niki

Introduction: Silent somatotroph Pituitary Neuroendocrine Tumours (PitNETs) are extremely rare (2−3% of surgically treated pituitary tumours) and data on their natural history and outcomes are scarce.Aim: To review systematically the cases of these tumours presenting in our Centre.Patients and methods: Patients with this diagnosis were identified from our Pituitary Registry and clinical/laboratory/imaging data were collected ...

ea0065p295 | Neuroendocrinology | SFEBES2019

Review of pituitary metastases diagnosed in a large pituitary centre

Lithgow Kirstie , Siqueira Izel , Ayuk John , Toogood Andrew , Gittoes Neil , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ahmed Shahzada , Khan Neelam , Meade Sara , Sanghera Paul , Paluzzi Alex , Tsermoulas George , Karavitaki Niki

Background: Metastatic disease in the pituitary (PM) is uncommon and the published literature mainly involves case reports and small case series. We aimed to analyze presenting manifestations and outcomes of patients diagnosed with PM in our pituitary centre.Methods: Retrospective review of our Pituitary Registry to identify patients with PM from 2006 to present. Clinical, radiological, and pathological data were collected and analysed.<p class="abst...

ea0065p315 | Neuroendocrinology | SFEBES2019

The spectrum of testosterone levels in males with functioning gonadotroph adenomas: report of three cases

Fountas Athanasios , Samperi Irene , Webster Rachel , Asia Miriam , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ayuk John , Toogood Andy , Gittoes Neil , Karavitaki Niki

Introduction: Functioning gonadotroph adenomas (FGAs) are very rare tumours secreting biologically active gonadotropins. In males, typically, FSH levels are elevated, whereas LH and testosterone are variable. Herein, we present three males with elevated, normal or low testosterone at diagnosis.Cases: Case 1:42-year-old man with two-year history of visual impairment. Bitemporal hemianopia was confirmed. Imaging showed macroadenoma compressing optic chiasm...