Searchable abstracts of presentations at key conferences in endocrinology

ea0013p171 | Diabetes, metabolism and cardiovascular | SFEBES2007

Abdominal obesity is associated with a decreased hepatic mRNA expression of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) in patients with non-alcoholic steatohepatitis (NASH)

Konopelska Sarah , Kienitz Tina , Pirlich Matthias , Bauditz Juergen , Stewart Paul M , Hughes Beverly , Lochs Herbert , Strasburger Christian J , Quinkler Marcus

Background: Non-alcoholic fatty liver disease (NAFLD) is recognized as common liver disorder that represents the hepatic manifestation of the metabolic syndrome including visceral obesity, type 2 diabetes, insulin resistance and hyperlipidemia. Non-alcoholic steatohepatitis (NASH) is the progressive form of liver injury with the risk for progressive fibrosis, cirrhosis and end-stage liver disease. The pathophysiology that leads to NAFLD and NASH is not well understood. We hypo...