Searchable abstracts of presentations at key conferences in endocrinology

ea0016p610 | Reproduction | ECE2008

Quantitative determination of aromatase and 5-α reductase mRNA and polymorphisms in the aromatase and 5-α reductase genes in idiopathic hirsutism

Dundar Munis , Okay Caglayan A , Baysal Nuran Ahu , Tanriverdi Fatih , Ozkul Yusuf , Unluhizarci Kursad , Kelestimur Fahrettin

Objective: Hirsutism, affects between 5% and 10% of women during reproductive age. Hirsutism associated with normal ovulatory function and normal circulating androgen concentrations is defined as idiopathic hirsutism and little information is available regarding the molecular pathogenesis.Aim: Significance of polymorphisms of the genes involved in androgen/oestrogen biosynthesis (SRD5A2,CYP19) and their expressions inmodulating the susceptibility ...