Endocrine Abstracts

Introduction: COVID-19 caused by SARS-COV-2 infection can lead to multi-organ injuries and significant mortality in severe and critical patients, especially among those individuals with type 2 diabetes. The aim of our study was to assess associations between severe COVID-19 pneumonia and clinical and biological characteristics of patients with type 2 diabetes.Methods: This was a retrospective and descriptive study including 40 Tunisians patients hospital...

Introduction: Renal cell carcinoma (RCC) is the most common type of malignant renal tumors in adults. It is often difficult to detect it precociously since early-stage renal tumors are usually asymptomatic and non-palpable. We report a case of RCC revealed by acute adrenal insufficiency (AAI).Case report: Mr. A.B, 46 years old, 30 pack-year smoker, with a medical history of gout treated with Allopurinol, was admitted to our department for acute adrenal i...

Introduction: The COVID-19 pandemic had a significant emotional and psychological impact on populations worldwide, especially vulnerable people with chronic diseases such as diabetics. The objective of our study was to assess the quality of life and psychological distress of diabetic patients and to study patients’ attitudes towards managing their diabetes.Methods: We conducted a cross sectional descriptive study involving 60 diabetic patients follo...

Introduction: Hyponatremia is a commonly associated with atypical pneumonia. One of its pathophysiological mechanisms is inappropriate antidiuretic hormone secretion(SIADH). We describe the case of a patient presenting an SIADH caused by COVID19 infection.Observation: We report a case of a 70-year-old man, known to have well-controlled hypertension, with a medical history of cavum’s neoplasia treated with radiotherapy and hypothyroidism post thyroid...

Introduction: Precocious puberty (PP) is a rare pathology involving approximatively 0.2% of girls and less than 0.05% of boys and is defined as the appearance of secondary sex characteristics before 8 years of age in girls and before 9 years of age in boys. We report an unusual case of a patient who presents a precocious puberty associated to a primary adrenal insufficiency.Case presentation: We describe a case of a 7-year and 4 months old girl referred ...

Introduction: Patients with hypothyroidism usually gain weight, and those with hyperthyroidism lose weight. Body weight changes related with thyroid dysfunction support the idea that thyroid hormones have an effect on body weight and body composition. The aim of our study was to describe the clinical profile and body composition of Tunisian patients who were newly diagnosed with hypothyroidism.Methods: This was a cross-sectional and descriptive study inc...

Introduction: Hemochromatosis is a disorder caused by an excess of iron deposition in the parenchymal cells that leads to organ dysfunction. In patients with secondary hemochromatosis due to multiple blood transfusions, endocrinopathies such as diabetes mellitus, hypopituitarism frequently develop.Herein we report the case of a patient with B-thalassemia major who developed diabetes mellitus, hypopituitarism and primary hypoparathyroidism due to secondar...

Introduction: Mixed gonadal dysgenesis with 45X/46XY mosaicism is considered to be a rare disorder of sex development. This condition is characterized by a phenotypically very heterogeneous clinical presentation. In fact, the individuals with 45X/46XY mosaicism ranged from phenotypically normal men with azoospermia, going through individuals with genital ambiguity, to women with Turner syndrome.Herein, we describe a phenotypically Turner-like female with...

Introduction: Simultaneous occurrence of acute pancreatitis and diabetic ketoacidosis represents a very rare complication of antipsychotic medications.Herein we report the case of acute pancreatitis and diabetic ketoacidosis in a non-diabetic patient while on treatment with haloperidol, chlorpromazine and carbamazepineCase report: Mr. Z A is a 50-year-old non-diabetic man who was diagnosed with psychotic disorder and treated with h...

Introduction: Riedel thyroiditis is a rare form of infiltrative and fibrotic disease of the thyroid which may involve neighbouring tissues. The main differential diagnosis of Riedel thyroiditis includes malignant tumors and fibrosing Hashimoto’s thyroiditis.Herein, we report a case of concurrent Riedel’s disease and Hashimoto’s thyroiditis.Observation: A 45-year-old woman was diagnosed with goiter and hypothyroidism....