Endocrine Abstracts

Introduction: COVID-19 caused by SARS-COV-2 infection can lead to multi-organ injuries and significant mortality in severe and critical patients, especially among those individuals with type 2 diabetes. The aim of our study was to assess associations between severe COVID-19 pneumonia and clinical and biological characteristics of patients with type 2 diabetes.Methods: This was a retrospective and descriptive study including 40 Tunisians patients hospital...

Introduction: Renal cell carcinoma (RCC) is the most common type of malignant renal tumors in adults. It is often difficult to detect it precociously since early-stage renal tumors are usually asymptomatic and non-palpable. We report a case of RCC revealed by acute adrenal insufficiency (AAI).Case report: Mr. A.B, 46 years old, 30 pack-year smoker, with a medical history of gout treated with Allopurinol, was admitted to our department for acute adrenal i...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder most commonly caused by a single adenoma of the parathyroid gland and rarely related to ectopic thymic parathyroid adenoma.Observation: 1st case: we report a case of a 46-year-old woman, diagnosed with PHPT. Scintigraphy concluded to a left inferior parathyroid adenoma. She underwent a focal parathyroid surgery and the adenoma was located in the thymus. The histopa...

Introduction: Paraganglioma is a rare neuroendocrine neoplasm which tends to develop in the extra-adrenal glands. Paraganglioma in the bladder is extremely rare and accounts for 0.06% of all bladder tumors Herein we report a case of paraganglioma that was mistaken for urothelial carcinoma and revealed by an intra-operative hypertensive crisis with bradycardia.Case presentation: A 48-year-old woman was referred to the urology department for intermittent t...

Introduction: The COVID-19 pandemic had a significant emotional and psychological impact on populations worldwide, especially vulnerable people with chronic diseases such as diabetics. The objective of our study was to assess the quality of life and psychological distress of diabetic patients and to study patients’ attitudes towards managing their diabetes.Methods: We conducted a cross sectional descriptive study involving 60 diabetic patients follo...

Introduction: Hyponatremia is a commonly associated with atypical pneumonia. One of its pathophysiological mechanisms is inappropriate antidiuretic hormone secretion(SIADH). We describe the case of a patient presenting an SIADH caused by COVID19 infection.Observation: We report a case of a 70-year-old man, known to have well-controlled hypertension, with a medical history of cavum’s neoplasia treated with radiotherapy and hypothyroidism post thyroid...

Introduction: Precocious puberty (PP) is a rare pathology involving approximatively 0.2% of girls and less than 0.05% of boys and is defined as the appearance of secondary sex characteristics before 8 years of age in girls and before 9 years of age in boys. We report an unusual case of a patient who presents a precocious puberty associated to a primary adrenal insufficiency.Case presentation: We describe a case of a 7-year and 4 months old girl referred ...

Introduction: Patients with hypothyroidism usually gain weight, and those with hyperthyroidism lose weight. Body weight changes related with thyroid dysfunction support the idea that thyroid hormones have an effect on body weight and body composition. The aim of our study was to describe the clinical profile and body composition of Tunisian patients who were newly diagnosed with hypothyroidism.Methods: This was a cross-sectional and descriptive study inc...

Introduction: Primary hyperparathyroidism (PHPT) is typically characterized by elevated serum calcium associated with elevated or non-suppressed levels of parathyroid hormone (PTH). These biochemical features are both known to affect the cardiovascular (CV) system. There is a conflicting debate regarding the CV manifestations of PHPT. the aim of our study is to evaluate the cardiovascular profile in patients with PHPT.Methods: We conducted a retrospectiv...

Introduction: The development of the Covid-19 pandemic infection, which started in March 2020 in Tunisia, has impacted all medical specialties. Endocrine care professionals were part of this battle, as many patients with endocrine diseases including primary hyperparathyroidism (PHPT) were also affected by the pandemic. the aim of our study was to evaluate the Impact of the Covid19 pandemic on patients with PHPT.Methods: This is a retrospective descriptiv...