Searchable abstracts of presentations at key conferences in endocrinology

ea0051p030 | Miscellaneous/other | BSPED2017

Audit of the management of patients with Turner’s syndrome in Northern Ireland

Beckett Rachel , Abid Noina

Introduction: In 2009, the Turner’s Syndrome Support Society UK released a checklist for the management of Turner’s Syndrome patients. The aim of this audit was to evaluate how well we are doing as a Tertiary Paediatric endocrine unit in meeting these required standards of care.Method: We performed a retrospective audit in June 2016 of patients diagnosed with Turner’s Syndrome in our unit between 2007 and 2015 using the Electronic Care Rec...

ea0085dpd1.4 | Diabetes and COVID Symposium | BSPED2022

‘Proving causation?’: antibody studies in covid related diabetes

Beckett Rachel , Stewart Caroline

Background: Population data has shown an increased incidence in Type 1 Diabetes Mellitus (T1DM) following pandemic influenza A (H1N1). Worldwide studies have shown an increase in the incidence of T1DM in 2020 and 2021. Both locally and regionally in Northern Ireland we noticed a similar increase and decided to investigate further.Method: From March 2021 we tested newly diagnosed T1DM patients in Antrim Area Hospital for Anti-SARS-CoV-2 antibodies. If ant...

ea0085oc4.2 | Oral Communications 4 | BSPED2022

Treatment-induced neuropathy of diabetes: a case report

McKenna Martha , Beckett Rachel

Case report: A previously well 16 year old female presented with a one day history of being unwell with agitation and confusion on the background of a three month history of polydipsia and polyuria. Initial biochemistry was in keeping with severe diabetic ketoacidosis (DKA): pH-6.75, HC03- 2.6 mmol/l, blood glucose- 21 mmol/l and ketones >4 mmol/l. Hypokalaemia of 3.3 mmol/l. She was admitted to ICU given the severity of DKA, biochemical disturbance and altered mental stat...

ea0066p15 | Bone | BSPED2019

Not your typical rickets case

Beckett Rachel , Heffernan Emmeline

Introduction: Rickets was once considered to be a disease of the Victorian Era but it has become increasingly common in recent years. The most common cause is Vitamin D deficiency; however it is important to investigate for rarer causes if Vitamin D deficiency has been excluded.Case report: A healthy, Caucasian 3 year old girl was referred due to bowing of her femora, apparent since she started walking at 13 months. She was reported to be clumsy and tire...

ea0045p29 | Diabetes | BSPED2016

Audit on metabolic effect of insulin pump therapy vs. pen for children with Type 1 Diabetes

Beckett Rachel , Abid Noina

Background: Insulin pump therapy has been linked to improved HbA1c levels, reduced frequency of severe hypoglycaemic episodes and reduced rates of Diabetic Ketoacidosis compared to treatment with multiple daily injections. Insulin pump therapy was started in 2008 in our unit.Aims: To compare the metabolic effect of insulin pump therapy vs multiple daily injections via pen devices in children with type 1 diabetes in our unit.Method:...

ea0045p30 | Diabetes | BSPED2016

A case of neonatal Diabetes: Diagnostic and management challenges

Beckett Rachel , Abid Noina

We present a patient who was incidentally diagnosed with neonatal diabetes at 4 months of age. Due to his small size his treatment has posed a number of challenges for our team.Case Report: A 4 month old boy presented to the Emergency Department with a petechial rash on his legs. Investigations revealed elevated blood glucose of 26.7 mmol/l but a normal pH of 7.39. He had glycosuria but no ketonuria. There was no history of weight loss or osmotic symptom...

ea0065p214 | Metabolism and Obesity | SFEBES2019

Hypoglycaemia screen (hypopak) quality improvement audit

Spence Kirsty , Beckett Rachel , Hamilton Gillian , Alcheikh Mohammad , Heffernan Emmeline , Abid Noina , O'Sullivan Siobhan , Connolly Grainne , McDonnell Margaret

In Northern Ireland hypopaks (contains samples for glucose, lactate, hydroxybutyrate, insulin, growth hormone (GH), cortisol, amino acids, organic acids and acylcarnitines) are used to investigate hypoglycaemia in children. We aimed to assess the appropriateness of hypopak requests, to determine their usefulness in diagnosing endocrine and metabolic conditions and to determine if GH is helpful. Data for hypopaks received between 01 April 17 and 31 March 18 was analysed. Hypopa...

ea0066p63 | Learning from Mistakes and Miscellaneous | BSPED2019

The use of ‘Hypopaks’ in the investigation of hypoglycaemia in children

Beckett Rachel , Spence Kirsty , Hamilton Gillian , Alcheikh Mohammad , O'Sullivan Siobhan , Connolly Grainne , McDonnell Margaret , Abid Noina , Heffernan Emmeline

Introduction: When hypoglycaemia (blood glucose <2.6 mmol/l) is detected in a child a ‘Hypopak’ is sent, which tests for blood glucose, lactate, hydroxybutyrate, insulin, growth hormone, cortisol, amino acids, acylcarnitines, and urine organic acids. We aimed to determine whether samples were sent appropriately and completely, and whether a diagnosis ensued.Methods: All Hypopak samples received by the laboratory between 1/4/17 and 31/3/18 w...