ea0081p403 | Pituitary and Neuroendocrinology | ECE2022
Fellinger Paul
, Beiglboeck Hannes
, Pfleger Lorenz
, Smajis Sabina
, Gajdosik Martin
, Marculescu Rodrig
, Vila Greisa
, Winhofer Yvonne
, Kautzky-Willer Alexandra
, Krebs Michael
, Krssak Martin
, Wolf Peter
Background: Growth hormone (GH) plays an important role in modifying body composition. In acromegaly, a state of chronic GH/IGF-I excess, visceral and ectopic fat mass, especially in the liver, are significantly reduced. The aim of this study was to investigate the impact of GH/IGF-I on hepatocellular lipid content (HCL) and energy metabolism in a non-acromegalic cohort of patients with and without non-alcoholic fatty liver disease (NAFLD).Methods: We pe...