Searchable abstracts of presentations at key conferences in endocrinology

ea0081p403 | Pituitary and Neuroendocrinology | ECE2022

GH/IGF-I impact hepatic lipid accumulation in non-acromegalic individuals with and without non-alcoholic fatty liver disease

Fellinger Paul , Beiglboeck Hannes , Pfleger Lorenz , Smajis Sabina , Gajdosik Martin , Marculescu Rodrig , Vila Greisa , Winhofer Yvonne , Kautzky-Willer Alexandra , Krebs Michael , Krssak Martin , Wolf Peter

Background: Growth hormone (GH) plays an important role in modifying body composition. In acromegaly, a state of chronic GH/IGF-I excess, visceral and ectopic fat mass, especially in the liver, are significantly reduced. The aim of this study was to investigate the impact of GH/IGF-I on hepatocellular lipid content (HCL) and energy metabolism in a non-acromegalic cohort of patients with and without non-alcoholic fatty liver disease (NAFLD).Methods: We pe...