Endocrine Abstracts

Introduction: We present a case of neurosarcoidosis presenting with anterior hypopituitarism and hypothalamic syndrome.Case Report: A 38-years old Caucasian woman presented from primary care with six-month history of secondary amenorrhoea. Additionally she reported non-specific tiredness, postural dizziness, nausea and abdominal pains. Over the same period she noticed progressive weight gain of three stones, increased somnolence, lethargy and excessive s...

Introduction: Isolated vomiting is a rare often forgotten presentation of Graves’s disease and can lead to delayed diagnosis. Multiple case reports quote vomiting in thyrotoxicosis co-presenting with Addisonian crisis, diabetic ketoacidosis or with abnormal liver function and jaundice. Another common association is hyperemesis gravidarum. Vomiting in paraneoplastic hyperthyroidism occurs through a similar mechanism of beta-HCG secretion, mainly related to germ-line tumour...

Case history: A 70 years old man with longstanding resistant hypertension on five antihypertensive agents, type two diabetes and raised BMI at 35.6 was referred to the endocrinology clinic for exclusion of possible Cushing’s disease. Clinically he had truncal obesity with plethoric face but no telangiectasia, easy bruising, purple striae or myopathy.Investigations: Endocrine examinations revealed normal 24 h urine free cortisol levels on two separat...

Introduction: We conducted a retrospective audit of emergency management of hypercalcaemia presenting to the acute medical team and compared our practice against the Society for Endocrinology guidelines September 2016.Method: 53 adult patients with 59 corresponding medical admissions were identified from tracking all biochemistry samples with corrected calcium (cCa) ≥3.0 mmol/l processed between August 2015 and July 2016 trustwide. We conducted a r...

Objective: To assess the effect of antithyroid drug pretreatment on radioiodine (I-131) treatment outcomes for benign thyroid disease.Method: Retrospective analysis of all patient records on the clinical database that underwent I-131 treatment for benign thyroid disease between 1989 and 2007.Results: About 544 patients were identified, 98 males (18%) and 446 females (82%). The mean age was 54 years (11-88). 464 patients (85.3%) we...