Endocrine Abstracts

Background: Thyroid nodules diagnosed as Bethesda category IV (follicular neoplasm/suspicious for follicular neoplasm (FN/SFN)) are recommended for surgery. However, only 25% of these nodules turn to be malignant on histopathology. Therefore, selection of nodules for surgery diagnosed as Bethesda category IV is important. We aimed at to define the predictive factors for malignancy and predictive risk indices for selection of surgery.Method: The records o...

Introduction: Parathyroid adenomas are rarely large in size. Here, we present a giant cystic parathyroid adenoma presented with pancytopenia.Case report: Twenty two years old female presented with fatigue, bone pain, polyuria, a lump in the neck and pancytopenia. She had a pulsatile mass on the right side of the neck which compressed her trachea. She was evaluated by Hematology since her Hb was 4.7 g/dl, WBC was 2200 u/l platelet count was: 69 000 u/l. B...

Introduction: The aldosterone-to-renin ratio (A/R) is the most frequently used screening test for primary hyperaldosteronism (PH) and a confirmation test is recommended when it is high. We aimed to determine the frequency of PH in patients with high A/R and investigated possible clinical features that might help to prevent unnecesary confirmation tests.Method: Patients who underwent saline infusion test because of high A/R (>3.8) were retrospectively...

Introduction: Subacute thyroiditis is an iflammatory disease of the thyroid gland characterized by pain, tenderness and swelling in the neck. Less frequently, it may present with painless or silent thyroiditis that occurs spontaneously or in the postpartum period. In a few studies in the literature, urinary iodine was reported to be high in patients with postpartum thyroiditis, but it was not evaluated in patients with subacute thyroiditis. We aimed to evaluate urinary iodine ...

Introduction: Familial Mediterranean Fever (FMF) is an autosomal recessive hereditary disease characterized by fever and inflammation of serous membranes. The most important complication of FMF is amyloidosis which has significant role in the prognosis. It is unclear how endocrine system hormones are affected in FMF. We present adrenal insufficiency in a an FMF patient without amyloidosis.Case: A 39 years old male patient who had been diagnosed with FMF ...

Introduction: In our country, some health institutions are allowed to constitute additional service buildings/centers in order to increase the accessibility to outpatient services and decrease the crowdiness in hospitals. We aimed to investigate the satisfaction of the patients evaluated in our endocrinology and metabolism diseases center-ENDOOTEM (Endocrinology-Nuclear Medicine-Diabetes-Obesity-Osteoporosis-Thyroid Diagnosis and TreatmentCenter)- which serves as a part of our...

Introduction: Prolactin is a multifunctional pituitary hormone. The effect of prolactin on platelet activation is not well understood. Prolactinomas are the most common type of pituitary adenomas, and they are medically responsive to dopamine agonists. Mean platelet volume (MPV) is a marker of platelet function and activation. The aim of this study was to evaluate MPV values before and 6 months of cabergoline treatment when normoprolactinemia was achieved.<p class="abstext...

Background: Osteoporosis is a common problem in postmenoausal women. There is limited data about the physiological importance of endogenous testosterone on bone mineral density (BMD) in older women is poorly understood.Aim: The aim of this study was to evaluate association of endogeneous testosterone with BMD and BMI.Materials-methods: This cross-sectional study included 64 patients (45–85 year) postmenopausal women; their dem...

Introduction: Pregnancy or lactation related osteoporosis (PLO) is very rare. It usually occurs in the third trimester or in the early post partum period and manifestations are severe back pain and loss of height due to vertebral fractures. Its etiology is not well understood. Classical treatment is cessation of lactation, calcium and Vit-D supplementation and biphosphanates in chosen cases. All osteoporosis drugs are approved mainly for post-menouposal osteoporosis a...

Background: Diabetes is very common disorder. Many studies have shown that patients with diabetes mellitus have incresing trombotic complications both arterial and venous trombosis. Bad control diabetes increases risk of trombosis. Recent reports have shown that shortened APTTs and increased fibrinogen indicate procoagulan situations. In this study, we aimed to evaluate whether chronic hyperglisemia or bad control diabetes causes trombosis which is reflected by shortened APTTs...