Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep418 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Vitamin D levels in newly diagnosed type I diabetes mellitus and relationship with organ specific autoimmune disorders

Efe Belgin , Akdere Gonca , Yorulmaz Goknur

Based on the effects of Vitamin D on immune system it has been suggested that vitamin D may play a role in the pathogenesis of type I diabetes mellitus (T1D) and other organ specific autoimmune disorders. In our study, we aimed to show the effect of Vitamin D deficiency in the development of newly diagnosed T1D and other autoimmune disease that may associated with T1D such as autoimmune thyroid disease (ATD), celiac disease, Addison’s disease, vitiligo and atrophic gastri...

ea0020p21 | Adrenal | ECE2009

Bilateral macronodular adrenal hyperplasia versus bilateral micronodular adrenal hyperplasia

Kebapci Nur , Efe Belgin , Kebapci Mahmut

Bilateral macronodular or micronodular adrenal hyperplasias are related to ACTH-independent or ACTH-dependant pathologies. ACTH-independent bilateral macronodular adrenal hyperplasia (AIMAH) and primary pigmented adrenocortical disease (PPNAD) are classical but rare examples of ACTH-independent pathologies, causing Cushing Syndrome. PPNAD is presented as bilateral micronodular adrenal hyperplasia.On the other hand, inherited defects in the enzymatic step...

ea0020p284 | Clinical case reports and clinical reports | ECE2009

Common variable immune deficiency as a rare cause of osteoporosis

Onbasi Kevser , Kebapci Nur , Efe Belgin

A 27 year-old-man was admitted to our hospital with pain in the back. Bone mineral density evaluation revealed severe osteoporosis at L1–L4 vertebrae, as well as on femur, too. Secondary osteoporosis reasons like thyrotoxicosis, glucocorticoid therapy, hypercortisolemia, hypercalciuria, hyperparathyroidism were excluded. Laboratory examination of the patient revealed to a hypoglobulinemia. Further evaluation of the immunoglobulin levels were in concordance with panhypoglo...

ea0049ep90 | Adrenal medulla | ECE2017

Pheochromocytoma in pregnancy

Efe Belgin , Yorulmaz Goknur , Alaguney Sevil , Canaz Funda , Badak Bartu

Introductıon: Pheochromocytoma is a tumor originating from the chromaffin cells. These tumors secrete catecholamines which act on target organs and cause hypertensive crises. They are rare during pregnancy, and a differential diagnosis must be carried out mainly with pregnancy-induced hypertension.Case: A 27-year-old patient in week 17 of pregnancy admitted to our clinic with hypertension and 45×55 mm heterogeneous nodular lesion in left surren...

ea0049ep264 | Calcium & Vitamin D metabolism | ECE2017

Primary hyperparathyroidism in pregnancy

Efe Belgin , Yorulmaz Goknur , Alaguney Sevil , Badak Bartu

Introduction: Primary hyperparathyroidism is the most common cause of hypercalcemia in the general population. Hypercalcemia during pregnancy can result in significant maternal and fetal morbidity and mortality.Case: A 30-year-old pregnant female primigravida in the 31 weeks of gestation with complaint of obstinate constipation was admitted to our emergency department. In laboratory tests, hypercalcemia was detected. She was a Syrian refugee and was unab...

ea0022p109 | Bone/Calcium | ECE2010

Primary hyperparathyroidism at pregnancy

Yorulmaz Goknur , Kebapci Nur , Onbasi Kevser , Efe Belgin , Akalin Aysen

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

ea0020p276 | Clinical case reports and clinical reports | ECE2009

Possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 diabetes mellitus and severe insulin resistance in a case of Seckel syndrome

Kebapci Nur , Onbasi Kevser , Yorulmaz Goknur , Efe Belgin , Basmak Hikmet

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

ea0020p303 | Clinical case reports and clinical reports | ECE2009

Large intrathoracic goiter mimicking lung cancer

Onbasi Kevser , Akalin Aysen , Yorulmaz Goknur , Kebapci Nur , Efe Belgin

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

ea0020p319 | Clinical case reports and clinical reports | ECE2009

Dwarfism and female extenal genitalia due to congenital partial hypopituitarism in a 46XY Seckel syndrome with microcephaly and multiple skeletal deformities

Kebapci Nur , Efe Belgin , Yakut Ayten , Adapinar Baki , Basmak Hikmet

Seckel syndrome (SS) is a rare disorder of severe growth retardation and craniofacial-skeletal abnormalities. In scant number of reports, neonates had intact hypothalamic–pituitary–adrenal axis before they die because of cardiopulmonary abnormalities. We present an unique case of SS at the age of 18 years and discuss the possible explanations of his growth retardation and sex reversal.Case: A 18-year-old female presented with short stature and ...

ea0081ep720 | Pituitary and Neuroendocrinology | ECE2022

Clinical and laboratory features and management of pituitary apoplexy: Case series

Ozer Ozge , Kebapci Medine Nur , Akalın Aysen , Efe Belgin , Yorulmaz Goknur

Introduction: Pituitary apoplexy (PA) is a clinical emergency resulting from acute ischemia or bleeding of the pituitary gland. Complaints of patients are usuallay headache and vision problems. We tried to discuss the reasons for presentation, pituitary imaging and hormones of patients.Patients and Methods: 10 patients (5 men and 5 women), median age 53 years at diagnosis were retrospectively reviewed. FSH, LH, estradiol/testosterone, GH, IGF1, TSH, FT4,...