Searchable abstracts of presentations at key conferences in endocrinology

ea0014p23 | (1) | ECE2007

Human somatotrophic (GH) adenoma cells – interleukin (IL)-1β induces production of il-6 and il-8.

Diness Signe , Rasmussen Æse Krogh , Bendtzen Klaus , Kosteljanetz Michael , Feldt-Rasmussen Ulla

Aim: to establish a human in vitro system for the study of pituitary cells in culture and subsequently to study the influence of the pro-inflammatory cytokines interleukin (IL)-1β and tumour necrosis factor (TNF)-α on the function of the somatotrophic cells inclusive the ability of the cells to produce IL-6 and IL-8.Methods: Pituitary adenomas were obtained from hypophysectomies of patients with acromegaly. The tissue was enzymatically d...