Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep790 | Reproductive and Developmental Endocrinology | ECE2020

Clinical evaluation and genetic analysis of patients affected by premature ovarian insufficiency: Identification and characterization of a new mutation of the BMP-15

Orsolini Francesca , Ferrarini Eleonora , Agretti Patrizia , De Marco Giuseppina , Di Cosmo Caterina , Benelli Elena , Fruzzetti Franca , Tonacchera Massimo

Background: Premature ovarian insufficiency (POI) is an ovarian defect characterized from primary or secondaryamenorrhea, high levels of FSH (> 25 UI/l) and low levels of estrogen, which occurs before age 40.Objective: The aim of the study was to evaluate the clinical features and genetic causes of a group of 68 patients with POI.Methods: We performed anamnestic and clinical evaluation, hormonal and autoimmunity assessment, pel...

ea0011p685 | Reproduction | ECE2006

Serum levels of PSA do not change in healthy pre-menopausal and in menopausal women, but are increased in subjects with polycystic ovary syndrome (PCOS)

Alessandro Burelli AB , Elisabetta Rineladi ER , Rossana Cionini RC , Elena Benelli EB , Aldo Pinchera AP , Enrico Pucci EP

Background/aims: Prostatic specific antigen (PSA) is the best prostatic tumor marker in man; Recently PSA has been detected in a variety of tissues and fluids in women and is considered a marker of hyperandrogenism. However no precise information are avaible about the physiology of PSA in females. The goal of this study was to assess serum concentrations of PSA in healthy pre-menopausal women (healthy pre-menopausal group) and menopausal women (menopause group) and compare the...

ea0099p411 | Late-Breaking | ECE2024

Prevalence of hepatosteatosis in young women with polycystic ovary syndrome (PCOS)

Benetti Zaira , Buti Simona , Sciarroni Elisabetta , Pignata Luisa , Fiore Emilio , Salvati Antonio , Benelli Elena , Bagattini Brunella , Tonacchera Massimo

Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age, often characterized by obesity and insulin-resistance. NAFLD (Non-Alcoholic Fatty Liver Disease) is a metabolic disorder characterized by the accumulation of fat in the liver, in absence of alcohol consumption and other possible causes of hepatosteatosis. The association between hepatosteatosis and at least one cardio-metabolic risk factor is defined as MASLD (Metabolic Dysfunct...