Endocrine Abstracts

Background: Premature ovarian insufficiency (POI) is an ovarian defect characterized from primary or secondaryamenorrhea, high levels of FSH (> 25 UI/l) and low levels of estrogen, which occurs before age 40.Objective: The aim of the study was to evaluate the clinical features and genetic causes of a group of 68 patients with POI.Methods: We performed anamnestic and clinical evaluation, hormonal and autoimmunity assessment, pel...

Background/aims: Prostatic specific antigen (PSA) is the best prostatic tumor marker in man; Recently PSA has been detected in a variety of tissues and fluids in women and is considered a marker of hyperandrogenism. However no precise information are avaible about the physiology of PSA in females. The goal of this study was to assess serum concentrations of PSA in healthy pre-menopausal women (healthy pre-menopausal group) and menopausal women (menopause group) and compare the...

Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age, often characterized by obesity and insulin-resistance. NAFLD (Non-Alcoholic Fatty Liver Disease) is a metabolic disorder characterized by the accumulation of fat in the liver, in absence of alcohol consumption and other possible causes of hepatosteatosis. The association between hepatosteatosis and at least one cardio-metabolic risk factor is defined as MASLD (Metabolic Dysfunct...

Objectives: The association between thyroid function variations and body mass index (BMI) has been described in the adult population in several studies: higher TSH values and lower FT4 values, while still within reference range, have been correlated with higher BMI values. The aim of the study was to assess thyroid hormones variations in relation to body weight in pregnant women without thyroid diseases.Methods: In this prospective study, thyroid functio...