Searchable abstracts of presentations at key conferences in endocrinology

ea0005p97 | Diabetes, Metabolism and Cardiovascular | BES2003

Altered insulin sensitivity and secretion in sotos syndrome

Nag S , Bennett S , Gerrard J , Walker M , Ball S

Background: Sotos syndrome is an uncommon condition characterised by rapid growth, large body size and acromegaloid facies.There is limited data on metabolic abnormalities in Sotos syndrome.Aims: We investigated insulin sensitivity and secretion rates in a 22 year old girl with Sotos syndrome, prompted by the observation of a flat glucose response after an oral glucose challenge.Methods: Glucose tolerance was assessed with a 75g 2-h oral glucose tolerance test (OGTT), ...

ea0011p478 | Endocrine tumours and neoplasia | ECE2006

Functioning adrenocortical carcinoma and the clinical endocrinologist: toxic treatments and poor prognosis

Thomas RM , Bliss R , Richardson D , Johnson S , Turner S , Bennett S , Quinton R

Adrenocortical carcinoma (ACC) is a rare and highly malignant tumour with a poor prognosis with an incidence of 1 – 2 per million population per year. We report 2 cases of functioning ACC.Case 1: An 80 yr old with a history of hypertension, paroxysmal atrial fibrillation and cerebrovascular disease presented with leg ulcers, peripheral oedema, tiredness, weight gain, plethora and proximal myopathy. ACTH-independent Cushing’s syndrome was confir...

ea0004p9 | Clinical case reports | SFE2002


Bennett S , Quinton R

We present a case of acquired hypogonadotrophic hypogonadism (HH) in a 54-year-old man that illustrates the need for wider endocrine screening in such patients. Having undergone complete pubertal development as a teenager and subsequently fathered two children, the patient presented with a nine-month history of reduced libido, erectile dysfunction, hot sweats and headaches. His GP had diagnosed HH on the basis of a low testosterone with inappropriately low gonadotrophins. Exam...

ea0012p29 | Clinical case reports/Governance | SFE2006

Life threatening hypocalcemia after use of fleet phospho-soda in bowel preparation for routine colonoscopy – a case report

Jayapaul M , Winkley E , Haigh C , Bennett S

Fleet Phospho-soda is frequently used to prepare bowel for gastrointestinal investigations or surgery. We report an 85 year old male who had severe life threatening hypocalcemia after using fleet. He was admitted for bowel preparation for colonoscopy due to altered bowel habits, weight loss and anaemia. Clinical examination was unremarkable. His investigations showed Hb-12.0 gm/dl, normal renal function (Serum creatinine -105 μmol/l), normal liver function but for a raise...