Endocrine Abstracts

Rationale: Grave’s disease (GD) is the most common subtype of autoimmune hyperthyroidism, which can manifest with a variety of extrathyroidal clinical syndromes such as ophthalmopathy, pretibial myxedema (dermopathy), acropathy, cardiomyopathy, and encephalopathy. In very rare instances, GD can also be diagnosed following severe gastrointestinal symptoms such as dysphagia, heartburn, nausea and vomiting. We hereby describe a rare case of GD with digestive symptoms which w...

Irisin is a myokine correlated with lean body mass, despite its association with cardiovascular events (Mantzoros 2014). Increased muscle volume and lipoatrophy have been reported in female FPLD (Ji JCEM 214). Our aim was to determine whether irisin could help to distinguish certain lipodystrophic obesities from FPLD.Methods and patients: Circulating irisin levels (EIA Phoenix) were measured in 20 LMNA-related FPLD, 19 normal-weighed controls (H) and 13 ...

Introduction: The most common sellar lesions are mainly due to pituitary adenomas, craniopharyngiomas and benign cysts. Rathke’s cleft cyst (RCC) is a developmental sellar or suprasellar cystic lesion, which rarely becomes symptomatic. Here, we present an interesting case of intra sellar RCC, with a presenting feature of acute pituitary apoplexy.Case report: A 39 year old healthy women was referred to the emergency room for sudden headache and fatig...

We herein describe a 55-year-old woman who showed a dramatic improvement in glucose control following treatment for co-existing acromegaly and Cushing’s syndrome. The co-occurrence of acromegaly and Cushing’s syndrome in one individual is extremely rare. This patient was diagnosed as having diabetes mellitus 7 years ago. Afterwards, in spite of insulin therapy, her hyperglycemia could not be well controlled. Endocrinological and radiological examinations revealed sub...