Searchable abstracts of presentations at key conferences in endocrinology

ea0084op-02-09 | Oral Session 2: Pregnancy | ETA2022

Hypothyroidism and the risk of preeclampsia: A national and regional study of 1,014,775 pregnancies in denmark

Berg Hjelm Maja , Munk Sinding Marianne , Sorensen Anne , Handberg Aase , Linding Andersen Stine

Objectives: Maternal hypothyroidism in pregnancy has been proposed to increase the risk of preeclampsia, but uncertainties persist regarding the underlying causal mechanisms. Thus, it remains unclear if an increased risk of preeclampsia in hypothyroid pregnant women is caused by the lack of thyroid hormones or by the thyroid autoimmunity per se.Methods: We performed a national and regional study in the Danish population. The national study was r...

ea0084op-05-23 | Oral Session 5: Autoimmunity | ETA2022

Cut-offs for thyroid peroxidase and thyroglobulin antibodies in early pregnancy are not similar and may differ from non-pregnant individuals: evidence from 10,905 danish pregnant women

Linding Andersen Stine , Henrik Bruun Niels , Astrup Christensen Peter , Lykkeboe Simon , Handberg Aase , Bo Hansen Annebirthe , Berg Hjelm Maja , Knosgaard Louise , Maria Uldall Torp Nanna , Carle Allan , Scott Karmisholt Jesper , Bulow Pedersen Inge , Vestergaard Peter , Andersen Stig

Objectives: Thyroid disease in women of reproductive age is predominantly of autoimmune origin, and thyroid peroxidase antibodies (TPO-Ab) as well as thyroglobulin antibodies (Tg-Ab) are key markers of autoimmune hypothyroidism. Adding to this, much focus in pregnancy is on euthyroid women who are positive for thyroid autoantibodies. The observational findings are diverse, and evidence to substantiate the applied cut-offs for definition of thyroid autoantibody-positivity in ea...