Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep925 | Thyroid (non-cancer) | ECE2015

A case of primary hypothyroidism initially presenting with massive pericardial effusion

Apaydin Mahmut , Beysel Selvihan , Demirci Taner , Cakal Erman , Delibasi Tuncay

Introduction: Although pericardial effusion is a common finding in primary hypothyroidism, massive pericardial effusion or pericardial tamponade are rare. Herein, we describe a newly diagnosed case of primary hypothyroidism initially presenting with massive pericardial effusion.Case report: A 64 years old male patient attended to the emergency unit with worsening dyspnea over the past 1 month. ECG showed a low voltage QRS wave. Chest X-ray showed increas...

ea0041ep447 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

The association between the FTO gene and gestational diabetes mellitus

Beysel Selvihan , Alp Yunus , Alparslan Pinarli Ferda , Cakal Erman , Yesilyurt Ahmet , Delibasi Tuncay

Introduction: Common polymorphisms of the fat mass and obesity associated gene (FTO) is known to associate with increased obesity and diabetes mellitus type 2. This was the first study to investigate the association between the rs9939609 FTO gene polymorphism and gestational diabetes mellitus (GDM) in Turkish women.Patients and methods: The case-control study included 203 gestational diabetes and 191 non-diabetic pregnant controls. Anthropometric and bio...

ea0041ep688 | Female Reproduction | ECE2016

Endocan as a novel biomarker to evaluate cardiovascular risks in Polycystic Ovary Syndrome

Apaydin Mahmut , Beysel Selvihan , Caliskan Mustafa , Kizilgul Muhammed , Ozcelik Ozgur , Kan Seyfullah , Ozbek Mustafa , Cakal Erman , Delibasi Tuncay

İntroduction: Polycystic ovary syndrome (PCOS) is associated with risk of cardiovascular disease (CVD). Endocan is potential immunoinflammatory and endothelial dysfunction marker that may be linked to CVD. This study aimed to evaluate the risk of CVD in PCOS patients and to identify the novel biomarker for CVD risk.Material and methods: We analyzed 52 premenopausal women with PCOS and 59 healthy controls. Clinical, biochemical parameters and endoca...

ea0037ep517 | Diabetes (complications & therapy) | ECE2015

Tear function tests in pregnant women with gestational diabetes mellitus

Kan Seyfullah , Acar Ugur , Kizilgul Muhammed , Beyazyildiz Emrullah , Cankaya Ali Bulent , Apaydin Mahmut , Beysel Selvihan , Ozbek Mustafa , Delibasi Tuncay

Aim: Gestational diabetes mellitus (GDM) is a disorder which is described as impaired glucose tolerance which firstly occurs first time during pregnancy. We aimed to evaluate the tear function tests such as Schirmer, tear break-up time (TBUT), tear film osmolarity (TFO), and ocular surface disease index (OSDI) score in pregnant with GDM.Methods: Pregnant women with GDM and healthy pregnant who were matched in both age and gestational age were enrolled in...

ea0037ep313 | Calcium and Vitamin D metabolism | ECE2015

The effects of single high dose vs daily low dose oral cholecalciferol treatment on vitamin D levels and muscle strenght in posmenapousal women

Apaydin Mahmut , Can Asli Gencay , Kan Seyfullah , Beysel Selvihan , Demirci Taner , Caliskan Mustafa , Kizilgul Muhammed , Ozcelik Ozgur , Arslan Muyesser Sayki , Ozbek Mustafa , Cakal Erman , Delibasi Tuncay

Introduction: Vitamin D deficiency is a common health problem. Vitamin D supplements are used to improve vitamin D status. However, there are few data about what doses to give and how often to give. The aim of this study is to determine the effects of single high dose or daily low dose oral cholecalciferol (vitamin D3) on vitamin D levels and muscle strenght.Methods and design: 60 healthy postmenouposal women who had serum vitamin D levels wer...

ea0037ep801 | Pituitary: clinical | ECE2015

Analysis of the aetiology of hypopituitarism: the results from double centre study

Caliskan Mustafa , Basaran Mehtap Navdar , Beysel Selvihan , Arslan Muyesser Sayki , Ucan Bekir , Tuna Mazhar Muslum , Cakal Erman , Berker Dilek Sensoz , Guler Serdar , Delibasi Tuncay

Introduction: Hypopituitarism is commonly acquired in adult life and its main causes are pituitary tumors and/or their treatments, empty sella syndrome and etc.Patients and methods: A double centre, cross-sectional database study was performed in Turkish population for last 10 years to investigate the etiology of hypopituitarism. One-hundred forty nine patients were included (53% female and 47% male) with a mean age of 47.9±15.6 years (ranging from ...

ea0037ep968 | Thyroid (non-cancer) | ECE2015

The effect of thyroid hormone replacement on treatment schedule

Apaydin Mahmut , Beysel Selvihan , Kan Seyfullah , Ucan Bekir , Tutal Esra , Demirci Taner , Caliskan Mustafa , Kizilgul Muhammed , Ozbek Mustafa , Cakal Erman , Delibasi Tuncay

Introduction: Levothyroxine sodium (LT4) is widely used thyroid hormone to treat hypothyroidism. It is generally recommended to take it in the morning and hungry. Several studies about timing of thyroid hormone administration have shown different effects on TSH and FT4. The aim of this study is to determine the effects of timing of LT4 administration on TSH and the clinical outcomes.Method: The study group includes 65 pat...

ea0037ep1124 | Endocrine tumours | ECE2015

Evaluation of metabolic syndrome in patients with primary hyperparathyroidism

Caliskan Mustafa , Arslan Muyesser Sayki , Tutal Esra , Beysel Selvihan , Karakose Melia , Apaydin Mahmut , Ozcelik Ozgur , Kizilgul Muhammed , Bozkurt Nujen Colak , Cakal Erman , Ozbek Mustafa , Delibasi Tuncay

Aims: Primary hyperparathyroidism (PH) has been reported to be associated with increased insulin resistance, hypertension, dyslipidemia and cardiovascular inflammatory markers. The aims of this study were to evaluate the rate of metabolic syndrome (MS) and effect of parathormone, calcium and phosphorus levels to MS components in PH subjects.Methods: One hundred and fifty one subjects, 23 men and 128 women, aged 53±11.2 years with newly diagnosed PH ...

ea0037ep1294 | Clinical Cases–Thyroid/Other | ECE2015

Cervical paraganglioma ultrasonographically mimicking parathyroid adenoma: a case report

Beysel Selvihan , Caliskan Mustafa , Arslan Muyesser Sayki , Karakose Melia , Tutal Esra , Kan Seyfullah , Kizilgul Muhammed , Apaydin Mahmut , Cakal Erman , Ozbek Mustafa , Delibasi Tuncay

Introduction: Paragangliomas are neuroendocrine tumors arising from extra-adrenal chromaffin cells. Paragangliomas of the head and neck frequently originate from the paraganglionic system including the carotid bifurcation, middle ear and the ganglion nodosum of the vagus nerve. However, of paragangliomas of the head and neck, only 1–3% secrete hormones and majority are non-functional. Here, we describe a case of non-functional paraganglioma confused with parathyroid adeno...

ea0037ep1295 | Clinical Cases–Thyroid/Other | ECE2015

Concurrent mediastinal parathyroid carcinoma and parathyroid adenoma

Caliskan Mustafa , Beysel Selvihan , Tutal Esra , Ucan Bekir , Demirci Taner , Kan Seyfullah , Apaydin Mahmut , Kizilgul Muhammed , Saylam Guleser , Cakal Erman , Ozbek Mustafa , Delibasi Tuncay

Introduction: While mediastinal parathyroid carcinoma is a rare entity by itself, multiglandular coexistence of parathyroid carcinoma and adenoma represents an extremely rare condition. Herein, we report such a rare presentation of multiglandular parathyroid neoplasm with an ectopic carcinoma in the mediastinum and adenoma on the right side of neck in a patient with persistent primary hyperparathyroidism (PHP).Case report: A 38-year-old female patient wh...