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Endocrine Abstracts

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ea0032p901 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Efficacy and safety of lanreotide in combination with pegvisomant in clinical practice in patients with active acromegaly with monotherapy failure

Venegas Eva , Lucas Tomas , Marazuela Monica , Cuatrecasas Guillem , Galvez Maria Angeles , Romero Enrique , Morales Francisco , Webb Susan M , Biaggeti Betina , Diaz Juan Jose , Mato Jose Antonio , Vilchez Ricardo , Bernabeu Ignacio , Paja Miguel , Pico Antonio , Domingo Manuel Puig , Soto Alfonso , on behalf of ACROCOMB study group

Introduction: ACROCOMB is a retrospective Spanish Multicenter study, designed to evaluate the efficacy (extent of tumour control) and safety of lanreotide (LAN) treatment combined with pegvisomant (PEG) or cabergoline in acromegalic patients with monotherapy failure.Methods: patients with acromegaly treated with LAN+PEG (45% of ACROCOMB patients) at 44 Spanish Endocrinology Departments were analysed.Results: 40% of patients were ma...
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ea0099p528 | Pituitary and Neuroendocrinology | ECE2024

Predictors of diabetes remission after surgery in patients with acromegaly. a series of 604 cases

Pascual-Corrales Eider , Biaggeti Betina , Marazuela Monica , Puig-Domingo Manel , Rodriguez Berrocal Victor , Irigaray Ana , Novo Cristina , Calatayud Maria , Bernabeu Ignacio , Alvarez Escola Cristina , Tenorio Jimenez Carmen , Gonzalez-Molero Inmaculada , Iglesias Pedro , Blanco Concepcion , Paz de Miguel Novoa Maria , Lopez-Mezquita Torres Elena , Lamas Cristina , Aulinas Maso Ana , Gracia Gimeno Paola , Maria Recio Jose , Antonio Sampedro Nunez Miguel , Paja Fano Miguel , Dolores Moure Rodriguez Maria , Fajardo-Montanana Carmen , Cordido Fernando , Luis Menendez Torre Edelmiro , Carlos Percovich Juan , Garcia Centeno Rogelio , Camara Rosa , A Hanzu Felicia , Vicente Almudena , Gonzalez Fernandez Laura , Guerrero Fernando , Dolores Ollero M , Araujo Castro Marta

Aim: To investigate the impact of pituitary surgery on glucose metabolism and to identify predictors of diabetes remission after surgery in patients with acromegaly.Methods: A national multicenter retrospective study of acromegaly patients undergoing transsphenoidal surgery for the first time at 33 tertiary Spanish hospitals (ACRO-SPAIN study, n=604) was performed. Surgical remission was evaluated according to the 2000 and 2010 criteria. Glucose...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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