Searchable abstracts of presentations at key conferences in endocrinology

ea0016p526 | Obesity | ECE2008

The effect of fasting on substrate metabolism and growth hormone signaling

Moller Louise , Dalman Lisa , Norrelund Helene , Billestrup Nils , Otto Jorgensen Jens

Background: Fasting is associated with suppression of IGF-I production, which is likely to be the stimulator of GH secretion and the subsequent increase in lipolysis. The GH signalling events subserving this switch in the actions of GH have not been studied.Aim: To assess whole body substrate metabolism and GH signalling proteins in skeletal muscle and fat in healthy human subjects in the postabsorptive state and after 38 h of fasting.<p class="abste...